Evidence map›Paper›PMID 38650822›Full record

ArticleCureus2024

Examining the Efficacy of 38% Silver Diamine Fluoride in Halting Active Dental Caries Lesions Among Children: A Descriptive Study.

Ayesha Saleem, Afshan Manzoor, Amara Nazir, Humara Iqbal, Muhammad A Khan, Zohaib Ahmed, Mustafa Sajid, Muhammad Kashif

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ayesha SaleemOperative Dentistry, Nishtar Institute of Dentistry, Multan, PAK.
Afshan ManzoorOperative Dentistry, Bakhtawar Amin Dental College and Hospital, Multan, PAK.
Amara NazirOperative Dentistry, Bakhtawar Amin Medical and Dental College, Multan, PAK.
Humara IqbalOperative Dentistry, Multan Medical and Dental College, Multan, PAK.
Muhammad A KhanOral Medicine, Bakhtawar Amin Medical and Dental College, Multan, PAK.
Zohaib AhmedPeriodontology, Shahida Islam Medical and Dental College, Lodhran, PAK.
Mustafa SajidOperative Dentistry, Bakhtawar Amin Medical and Dental College, Multan, PAK.
Muhammad KashifOral Pathology, Bakhtawar Amin Medical and Dental College, Multan, PAK.
Karachi Medical and Dental College · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesDental caries, a prevalent issue among children, often leads to discomfort and potential complications. Utilizing caries-arresting treatments to slow down its progression offers a practical alternative. Previous research indicates that topical fluorides can deactivate and remineralize enamel caries. This study aims to evaluate the efficacy of 38% silver diamine fluoride (SDF) in halting active dental caries lesions in children. MATERIALS AND

methodsThis descriptive case series was conducted at the Operative Dentistry Department of the Nishtar Institute of Dentistry in Multan, Pakistan. We enrolled 753 patients aged three to nine years, of both genders, each with at least one cavitated lesion graded 3-6 according to the International Caries Detection and Assessment System (ICDAS). SDF was directly applied to dried and isolated teeth using a micro brush and left to absorb for up to two minutes (adjusted based on the child's cooperation), and parents were instructed to ensure the child refrained from eating or drinking for an hour post-application. Baseline examinations were performed by consultant restorative dentists, and reexaminations were conducted after two to three weeks by a consultant unaware of the study.

resultsThe study included children aged three to nine years, with a mean age of 6.02±1.35 years. The majority of patients (61.75%) were aged between three and six years. Among the 753 patients, 619 (82.20%) were male, and 134 (17.80%) were female, with a male-to-female ratio of 4.6:1. The efficacy of 38% SDF in arresting active dental caries lesions in children was observed in 720 (95.62%) patients.

conclusionThis study demonstrates that 38% SDF is highly effective in halting active dental caries lesions in children.

Indexed as

demineralizationdental cariesremineralizationsilver diamine fluoridetopical fluoride

Identifiers

PMID38650822
PMCPMC11033969
OpenAlexW4393113581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.