Evidence map›Paper›PMID 38650545›Full record

ArticleJournal of the European Academy of Dermatology and Venereology : JEADV2025

Paediatric cutaneous lymphomas including rare subtypes: A 40-year experience at a tertiary referral centre.

Silvia Alberti-Violetti, Gianluca Avallone, Cristiana Colonna, Gianluca Tavoletti, Luigia Venegoni, Valentina Merlo, Stefano Cambiaghi, Angelo V Marzano, Emilio Berti, Riccardo Cavalli

Open access · hybridAbstract read
In one paragraph

Article in Journal of the European Academy of Dermatology and Venereology : JEADV, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Cutaneous Hematologic Neoplasms in Children: Overview and Update.Dermatopathology (Basel, Switzerland) · 2026
    Review
  4. Paediatric cutaneous lymphomas including rare subtypes: A 40-year experience at a tertiary referral centre.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Article
  5. Skin lymphomas in childhood: We only see what we know, we only know what we see.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Article
  6. Subcutaneous Panniculitis-Like T-Cell Lymphoma in Children: Two Case Reports.Clinical, cosmetic and investigational dermatology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Silvia Alberti-ViolettiDermatology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0000-0001-7163-1035
Gianluca AvalloneDermatology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0000-0001-7253-2370
Cristiana ColonnaPediatric Dermatology Unit, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Gianluca TavolettiDermatology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0000-0001-8901-318X
Luigia VenegoniDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.ORCID https://orcid.org/0000-0002-1846-1206
Valentina MerloDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.ORCID https://orcid.org/0000-0003-1438-4052
Stefano CambiaghiPediatric Dermatology Unit, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Angelo V MarzanoDermatology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0000-0002-8160-4169
Emilio BertiDermatology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Riccardo CavalliPediatric Dermatology Unit, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
University of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary cutaneous lymphomas are neoplasms of the immune system with a distinct tropism for the skin and an absence of extracutaneous manifestations at the time of diagnosis. Studies focusing on cutaneous lymphomas in children and adolescents remain scarce and often do not encompass the rare subtypes.

objectivesTo address this knowledge gap by describing the clinical, histological and molecular characteristics of a large group of paediatric patients affected by primary cutaneous lymphoma. We also provided the Paediatric Primary Cutaneous Lymphoma Atlas that illustrates the clinicopathological spectrum of observed presentations, in the hope of supporting other physicians in the diagnostic process.

methodsRetrospective chart review of paediatric patients diagnosed with primary cutaneous lymphomas between 1980 and 2022 at the Paediatric Dermatology Unit of Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan.

resultsA total of 101 patients (58 males, 43 females) met the inclusion criteria. The most common subtypes were lymphomatoid papulosis (n = 48) and mycosis fungoides (n = 31). These were followed by primary cutaneous CD4

conclusionsOur findings shed light on the peculiar aspects and long-term outcomes of paediatric cutaneous lymphomas, particularly emphasizing their distinctive features in comparison to their adult counterparts and exploring the less common subtypes. Further larger-scale studies are warranted to better characterize these entities and to achieve a more rapid and accurate diagnosis.

Indexed as

Skin NeoplasmsTertiary Care CentersAdolescentChildChild, PreschoolFemaleHumansInfantLymphoma, B-Cell, Marginal ZoneLymphoma, FollicularLymphoma, T-CellLymphoma, T-Cell, CutaneousLymphomatoid PapulosisMaleMycosis FungoidesPanniculitis

Identifiers

PMID38650545
PMCPMC11664474
OpenAlexW4395048205

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.