Evidence map›Paper›PMID 38650449›Full record

SynthesisZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences2024

Efficacy and safety of tetrandrine in treatment of rheumatoid arthritis: a meta-analysis.

Juan Xu, Jichen Li, Yan Ye, Qingwei Zhao, Duo Lyu

Open access · diamondAbstract readMeta-Analysis
In one paragraph

Synthesis in Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Juan XuClinical Pharmacy, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. xujuan9953@126.com.
Jichen LiClinical Pharmacy, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Yan YeClinical Pharmacy, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Qingwei ZhaoClinical Pharmacy, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Duo LyuClinical Pharmacy, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. lvduo8905@zju.edu.cn.
First Affiliated Hospital Zhejiang University · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the efficacy and safety of tetrandrine in the treatment of rheumatoid arthritis.

methodsRandomized controlled studies of tetrandrine in the treatment of rheumatoid arthritis were searched in CNKI, VIP, Wanfang database, SinoMed, PubMed, Springer, Web of Science and Cochrane Central Register of Controlled Trails databases. A meta-analysis was conducted using R 3.5.3 software to evaluate the clinical outcomes, including the total effective rate, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), rheumatoid factor (RF), visual analogue scale (VAS), disease activity score (DAS), tender joint count (TJC), swollen joint count (SJC), and morning stiffness duration, as well as adverse events of rheumatoid arthritis patients.

resultsA total of 10 articles were included in the study. The meta-analysis indicated that tetrandrine significantly improved the total effective rate (

conclusionsTetrandrine is effective in the treatment of RA patients with a mild degree of adverse events.

Indexed as

Arthritis, RheumatoidBenzylisoquinolinesBlood SedimentationC-Reactive ProteinHumansRandomized Controlled Trials as TopicTreatment OutcomeBenzylisoquinolinesC-Reactive ProteintetrandrineClinical efficacyMeta-analysisRheumatoid arthritisSafetyTetrandrine

Identifiers

PMID38650449
PMCPMC11375499
OpenAlexW4395082969

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.