Evidence map›Paper›PMID 38650294›Full record

ArticleBioresources and bioprocessing2021

Effect of biosurfactant sophorolipids on Rhizomucor miehei lipase fermentation by Aspergillus oryzae.

Qianqian Zhang, Zhiyue Xiong, Lei Sun, Xiwei Tian, Guiwei Tian, Yiming Yang, Xu Li, Yonghong Wang, Ju Chu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioresources and bioprocessing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Qianqian ZhangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, P.O. box 329, Shanghai, 200237, People's Republic of China.
Zhiyue XiongState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, P.O. box 329, Shanghai, 200237, People's Republic of China.
Lei SunState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, P.O. box 329, Shanghai, 200237, People's Republic of China.
Xiwei TianState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, P.O. box 329, Shanghai, 200237, People's Republic of China.
Guiwei TianWilmar Biotechnology R&D Center Co., Ltd, Shanghai, 200137, China.
Yiming YangWilmar Biotechnology R&D Center Co., Ltd, Shanghai, 200137, China.
Xu LiState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, P.O. box 329, Shanghai, 200237, People's Republic of China. xuli@ecust.edu.cn.
Yonghong WangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, P.O. box 329, Shanghai, 200237, People's Republic of China.
Ju ChuState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, P.O. box 329, Shanghai, 200237, People's Republic of China. juchu@ecust.edu.cn.ORCID http://orcid.org/0000-0002-6406-1748
East China University of Science and Technology · CNShanghai CASB Biotechnology (China) · CN

Funding

the Fundamental Research Funds for the Central Universities, China JKF01211708, JKVF1211036the National Key Research Development Program of China 2021YFC2100205,2019YFA0904803
6 · The paper itself

Abstract

In this study, the effect of biosurfactant sophorolipids (SLs) on Rhizomucor miehei lipase (RML) fermentation by Aspergillus oryzae was investigated. With the exogenous addition of 0.3% (w/v) SLs in the initial medium, the RML activity reached 430.0 U/mL, an increase of 25.0% compared to the control group. Subsequently, the physiological metabolic responses of A. oryzae to the addition of SLs were further explored. The results showed that though SLs had almost no effect on the RML secretion, it would affect the morphology of the cells. During the late phase of the fermentation, the proportion of middle pellets, which was generally considered as an energetic and stable state for enzyme production was increased with the addition of SLs. Simultaneously, the viscosity of fermentation broth was reduced, which facilitated the increase of oxygen transfer, thereby improving the RML production. Finally, it could be found that the addition of SLs significantly increased the contents of precursor amino acids, especially for those rank first and second of the RML composition, and it could promote the synthesis of RML.

Indexed as

Amino acidAspergillus oryzaeMorphologyRhizomucor miehei lipaseSophorolipids

Identifiers

PMID38650294
PMCPMC10991578
OpenAlexW3176943114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.