Evidence map›Paper›PMID 38650195›Full record

ArticleBioresources and bioprocessing2021

Chitopentaose inhibits hepatocellular carcinoma by inducing mitochondrial mediated apoptosis and suppressing protective autophagy.

Chunfeng Zhu, Mengyao Zhao, Liqiang Fan, Xuni Cao, Quanming Xia, Jiachun Zhou, Hao Yin, Liming Zhao

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioresources and bioprocessing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Chunfeng ZhuSchool of Biotechnology, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, No. 130 Meilong Road, Shanghai, 200237, China.
Mengyao ZhaoSchool of Biotechnology, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, No. 130 Meilong Road, Shanghai, 200237, China. myzhao@ecust.edu.cn.
Liqiang FanSchool of Biotechnology, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, No. 130 Meilong Road, Shanghai, 200237, China.
Xuni CaoSchool of Biotechnology, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, No. 130 Meilong Road, Shanghai, 200237, China.
Quanming XiaSchool of Biotechnology, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, No. 130 Meilong Road, Shanghai, 200237, China.
Jiachun ZhouSchool of Biotechnology, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, No. 130 Meilong Road, Shanghai, 200237, China.
Hao YinOrgan Transplant Center, Shanghai Changzheng Hospital, Shanghai, 200003, China.
Liming ZhaoSchool of Biotechnology, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, No. 130 Meilong Road, Shanghai, 200237, China. zhaoliming@ecust.edu.cn.
East China University of Science and Technology · CNShandong University of Technology · CNShanghai Changzheng Hospital · CNShanghai Innovative Research Center of Traditional Chinese Medicine · CN

Funding

China Postdoctoral Science Foundation 2017M621392Fundamental Research Funds for the Central Universities 22221818014Open Project Funding of the State Key Laboratory of Bioreactor Engineering, ECUST ZDXM2019Shanghai PuJiang Program 18PJ1401900"Shu Guang" project of Shanghai Municipal Education Commission and Shanghai Education Development Foundation 15SG28
6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is one of the most prevalent and deadliest cancers. In this study, the anti-tumor effect of singular degree of polymerization (DP) chitooligosaccharides (COS) (DP 2-5) and the underlay molecular mechanisms were investigated on HCC cell line HepG2. MTT assay showed that (GlcN)

Indexed as

ApoptosisAutophagyChitooligosaccharidesHCCSingular DP

Identifiers

PMID38650195
PMCPMC10992246
OpenAlexW3139241947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.