Evidence map›Paper›PMID 38649647›Full record

ArticleEndocrine2024

Thyroid dysfunction in nonvalvular atrial fibrillation and clinical outcomes.

Zeni Chen, Huaibin Wan, Tingting Min, Shaohui Su, De-Guang Yang

Abstract read
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In one paragraph

Article in Endocrine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zeni ChenDepartment of Cardiology, the First Affiliated Hospital of Jinan University, Guangzhou, China.
Huaibin WanDepartment of Cardiology, Shenhe People's Hospital, the Fifth Affiliated Hospital of Jinan University, Heyuan, China.
Tingting MinDepartment of Cardiology, Dongguan People's Hospital, the First School of Clinical Medicine, Southern Medical University, Dongguan, China.
Shaohui SuDepartment of Cardiology, Dongguan People's Hospital, the First School of Clinical Medicine, Southern Medical University, Dongguan, China.
De-Guang YangDepartment of Cardiology, the First Affiliated Hospital of Jinan University, Guangzhou, China. yangguang98198@163.com.
Southern Medical University · CNFirst Affiliated Hospital of Jinan University · CNJinan University · CN

Funding

Science and Technology Projects in Guangzhou SL2024A03J00319
6 · The paper itself

Abstract

backgroundThyroid dysfunction's effects on those who have been diagnosed with atrial fibrillation have not been well investigated. We looked at how thyroid function among patients with pre-existing atrial fibrillation related to thromboembolic risk and clinical outcomes.

methodsWe gathered the medical information of patients diagnosed with nonvalvular atrial fibrillation (NVAF) between 2016 and 2020 at Dongguan People's Hospital. We then assessed the correlation between thyroid dysfunction and thrombotic risk (CHA

resultsOf 1329 patients were admitted, 82.6% were euthyroid, 7.4% had subclinical hyperthyroidism, 4.2% had subclinical hypothyroidism, and 6.7% had low triiodothyronine (T3) syndrome. Lower levels of total triiodothyronine (TT3) were linked to an increased risk of thromboembolism (P < 0.005). During a median follow-up period of 1.84 years, there were 608 clinical composite endpoint occurrences. In the adjusted model, Low T3 syndrome was linked to a higher risk of the clinical composite endpoint (HR, 1.68; 95% CI, 1.20-2.37; P < 0.05) in comparison to euthyroidism. Specifically, low T3 syndrome was linked to a higher risk of heart failure (HR, 1.52; 95%CI, 1.01-2.30; P < 0.05) and all-cause death (HR, 3.34; 95% CI, 1.76-6.36; P < 0.001).

conclusionLow T3 syndrome are linked to an increased risk of heart failure and all-cause death in individuals with NVAF. And Patients with NVAF and low TT3 levels have a higher risk of thromboembolism.

Indexed as

Atrial FibrillationAgedAged, 80 and overFemaleHumansHyperthyroidismHypothyroidismMaleMiddle AgedRisk FactorsThromboembolismThyroid DiseasesThyroid Function TestsTriiodothyronineTriiodothyronineAtrial fibrillationLow T3 syndromeSubclinical thyroid dysfunctionThromboembolismThyroid function

Identifiers

PMID38649647
OpenAlexW4394996811

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.