Evidence map›Paper›PMID 38649642›Full record

ArticleTropical animal health and production2024

Association of polymorphism in the promotor area of the caprine BMPR1B gene with litter size and body measurement traits in Damani goats.

Inayat Ullah, Rajwali Khan, Syed Muhammad Suhail, Ijaz Ahmad, Farhan Anwar Khan, Muhammad Shoaib, Kamran Farid, Amel Ayari-Akkari, Ekhlas Ali Morfeine

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Article in Tropical animal health and production, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Inayat UllahDepartment of Livestock Management, Breeding and Genetics, Faculty of Animal Husbandry and Veterinary Sciences, The University of Agriculture, Peshawar, Pakistan.
Rajwali KhanDepartment of Livestock Management, Breeding and Genetics, Faculty of Animal Husbandry and Veterinary Sciences, The University of Agriculture, Peshawar, Pakistan. rajwalikhan@aup.edu.pk.ORCID http://orcid.org/0000-0001-5191-3457
Syed Muhammad SuhailDepartment of Livestock Management, Breeding and Genetics, Faculty of Animal Husbandry and Veterinary Sciences, The University of Agriculture, Peshawar, Pakistan.
Ijaz AhmadDepartment of Livestock Management, Breeding and Genetics, Faculty of Animal Husbandry and Veterinary Sciences, The University of Agriculture, Peshawar, Pakistan.
Farhan Anwar KhanCollege of Veterinary Sciences, Faculty of Animal Husbandry and Veterinary Sciences, The University of Agriculture, Peshawar, Pakistan.
Muhammad ShoaibCollege of Veterinary Sciences, Faculty of Animal Husbandry and Veterinary Sciences, The University of Agriculture, Peshawar, Pakistan.
Kamran FaridDepartment of Livestock and Dairy Development (Extension) Government of Khyber Pakhtunkhwa, Peshawar, Pakistan.
Amel Ayari-AkkariBiology Department, College of Science, King Khalid University, P.O. Box 960, Abha, Saudi Arabia.
Ekhlas Ali MorfeineBiology Department, College of Science, King Khalid University, P.O. Box 960, Abha, Saudi Arabia.
The University of Agriculture, Peshawar · PKKing Khalid University · SAGovernment of Khyber Pakhtunkhwa · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to explore polymorphisms in the promoter region of the caprine BMPR1B (Bone morphogenetic protein receptor 1 beta) gene and its association with body measurement and litter size traits in Damani does. A total of 53 blood samples were collected to analyze the association between the BMPR1B gene polymorphism and 11 phenotypic traits in Damani female goats. The results revealed that three novel SNPs were identified in the promoter region of the caprine BMPR1B gene, including g.67 A > C (SNP1), g.170 G > A(SNP2), and g.501A > T (SNP3), among which the SNP1 and SNP2 were significantly (p < 0.05) associated with litter size and body measurement traits in Damani goats. In SNP1 the AC genotype could be used as a marker for litter size, and the CC genotype for body weight in Damani goats. In SNP2, the genotype GG was significantly (p < 0.05) associated with ear and head length. Therefore, we can conclude from the present study, that genetic variants AC and CC of the caprine BMPR1B gene could be used as genetic markers for economic traits through marker-assisted selection for the breed improvement program of the Damani goat.

Indexed as

Bone Morphogenetic Protein Receptors, Type IGoatsLitter SizePolymorphism, Single NucleotidePromoter Regions, GeneticAnimalsFemaleGenotypeIranBone Morphogenetic Protein Receptors, Type IAssociation analysisBMPR1B geneBody measurement traitsDamani goatsLitter size

Identifiers

PMID38649642
OpenAlexW4395012954

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.