Evidence map›Paper›PMID 38649488›Full record

ArticleNature2024

Multimodal cell atlas of the ageing human skeletal muscle.

Yiwei Lai, Ignacio Ramírez-Pardo, Joan Isern, Juan An, Eusebio Perdiguero, Antonio L Serrano, Jinxiu Li, Esther García-Domínguez, Jessica Segalés, Pengcheng Guo and 13 more

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 145 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
145citing papers in PubMed, 1 pooled it
31.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

145 citing papers in PubMed, 1 synthesis or guideline pooled it, 136 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. A who's who of cell types in skeletal muscle.Communications biology · 2026
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

85 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 6 institutions in 4 countries.

Yiwei Lai *BGI Research, Hangzhou, China.
Ignacio Ramírez-Pardo *Department of Medicine and Life Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain.
Joan Isern *Altos Labs, San Diego Institute of Science, San Diego, CA, USA.ORCID 0000-0002-1401-9779
Juan An *BGI Research, Hangzhou, China.
Eusebio Perdiguero *Department of Medicine and Life Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain.
Antonio L Serrano *Department of Medicine and Life Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain.
Jinxiu Li *BGI Research, Hangzhou, China.
Esther García-DomínguezFreshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia and CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain.ORCID 0000-0001-6276-4944
Jessica SegalésDepartment of Medicine and Life Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain.
Pengcheng GuoBGI Research, Hangzhou, China.
Vera LukesovaDepartment of Medicine and Life Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain.
Eva AndrésDepartment of Medicine and Life Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain.
Jing ZuoBGI Research, Hangzhou, China.
Yue YuanBGI Research, Hangzhou, China.
Chuanyu LiuBGI Research, Hangzhou, China.ORCID 0000-0003-2258-0897
José ViñaFreshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia and CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain.ORCID 0000-0001-9709-0089
Julio Doménech-FernándezServicio de Cirugía Ortopédica y Traumatología, Hospital Arnau de Vilanova y Hospital de Liria and Health Care Department Arnau-Lliria, Valencia, Spain.ORCID 0000-0001-9488-8159
Mari Carmen Gómez-CabreraFreshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia and CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain.ORCID 0000-0003-4000-1684
Yancheng SongDepartment of Orthopedics, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Longqi LiuBGI Research, Hangzhou, China.ORCID 0000-0002-5828-5542
Xun XuBGI Research, Hangzhou, China.ORCID 0000-0002-5338-5173
Pura Muñoz-CánovesDepartment of Medicine and Life Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain. pmunozcanoves@altoslabs.com.ORCID 0000-0002-7533-9047
Miguel A EstebanBGI Research, Hangzhou, China. miguelesteban@genomics.cn.ORCID 0000-0002-1426-6809
BGI Group (China) · CNFleet Science Center · USUniversitat de València · ESUniversitat Pompeu Fabra · ESFirst Affiliated Hospital of Guangdong Pharmaceutical University · CNHospital Arnau de Vilanova · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muscle atrophy and functional decline (sarcopenia) are common manifestations of frailty and are critical contributors to morbidity and mortality in older people

Indexed as

AgingMuscle, SkeletalSingle-Cell AnalysisAdolescentAdultAgedAged, 80 and overCell NucleusChromatinDisease SusceptibilityEpigenesis, GeneticFemaleFrailtyHumansMaleMiddle AgedChromatin

Identifiers

PMID38649488
PMCPMC11062927
OpenAlexW4394996717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.