ArticleCommunications biology2024
Salience network connectivity is altered in 6-week-old infants at heightened likelihood for developing autism.
Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Presymptomatic Biological, Structural, and Functional Diagnostic Biomarkers of Autism Spectrum Disorder.Journal of neurochemistry · 2025Pooled it
- Brain morphology network profiles in male and female youth with autism.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Alterations in Early Alpha-band Connectivity emerge in Infancy among children later diagnosed with Autism.medRxiv : the preprint server for health sciences · 2026Article
- Sensory Reactivity in Autism: Integrating Behavioural, Affective, Physiological, and Neural Dimensions.Current psychiatry reports · 2026Review
- Deciphering multiway multiscale brain network connectivity from birth to 6 months.Communications biology · 2026Article
- Fetal functional connectivity prospectively associates with autistic traits in toddlerhood.NeuroImage. Clinical · 2026Article
- Alterations in self-related brain networks in autism spectrum disorder: a systematic review of functional and structural magnetic resonance imaging studies.Psychoradiology · 2026Review
- Own-name processing in toddlers with autism spectrum disorder: ERP evidence from an auditory oddball paradigm.Frontiers in psychiatry · 2026Article
- Salience Network in Autism: preliminary results on functional connectivity analysis in resting state.European archives of psychiatry and clinical neuroscience · 2025Article
- The Long and Winding Road to Understanding Autism.NeuroSci · 2025Review
- Functional connectivity between the visual and salience networks and autistic social features at school-age.Journal of neurodevelopmental disorders · 2025Article
- Deciphering Multiway Multiscale Brain Network Connectivity: Insights from Birth to 6 Months.bioRxiv : the preprint server for biology · 2025Article
- Sensory-movement underpinnings of lifelong neurodivergence: getting a grip on autism.Frontiers in integrative neuroscience · 2025Article
- Early selective attention to the articulating mouth as a potential female-specific marker of better language development in autism: a review.Frontiers in psychology · 2025Article
- Salience network connectivity is altered in 6-week-old infants at heightened likelihood for developing autism.Communications biology · 2024Article
- Functional neural network connectivity at 3 months predicts infant-mother dyadic flexibility during play at 6 months.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Associations between thalamocortical functional connectivity and sensory over-responsivity in infants at high likelihood for ASD.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Converging evidence implicates disrupted brain connectivity in autism spectrum disorder (ASD); however, the mechanisms linking altered connectivity early in development to the emergence of ASD symptomatology remain poorly understood. Here we examined whether atypicalities in the Salience Network - an early-emerging neural network involved in orienting attention to the most salient aspects of one's internal and external environment - may predict the development of ASD symptoms such as reduced social attention and atypical sensory processing. Six-week-old infants at high likelihood of developing ASD based on family history exhibited stronger Salience Network connectivity with sensorimotor regions; infants at typical likelihood of developing ASD demonstrated stronger Salience Network connectivity with prefrontal regions involved in social attention. Infants with higher connectivity with sensorimotor regions had lower connectivity with prefrontal regions, suggesting a direct tradeoff between attention to basic sensory versus socially-relevant information. Early alterations in Salience Network connectivity predicted subsequent ASD symptomatology, providing a plausible mechanistic account for the unfolding of atypical developmental trajectories associated with vulnerability to ASD.
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