Evidence map›Paper›PMID 38649361›Full record

ArticleNature communications2024

Estimating the effects of temperature on transmission of the human malaria parasite, Plasmodium falciparum.

Eunho Suh, Isaac J Stopard, Ben Lambert, Jessica L Waite, Nina L Dennington, Thomas S Churcher, Matthew B Thomas

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eunho Suh *Center for Infectious Disease Dynamics, Department of Entomology, The Pennsylvania State University, University Park, PA, USA. eus57@psu.edu.ORCID http://orcid.org/0000-0003-1761-0019
Isaac J Stopard *MRC Centre for Global Infectious Disease Analysis, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-4612-5004
Ben LambertDepartment of Statistics, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-4274-4158
Jessica L WaiteCenter for Infectious Disease Dynamics, Department of Entomology, The Pennsylvania State University, University Park, PA, USA.
Nina L DenningtonCenter for Infectious Disease Dynamics, Department of Entomology, The Pennsylvania State University, University Park, PA, USA.
Thomas S ChurcherMRC Centre for Global Infectious Disease Analysis, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-8442-0525
Matthew B ThomasCenter for Infectious Disease Dynamics, Department of Entomology, The Pennsylvania State University, University Park, PA, USA.

Funding

Influence of temperature on malaria transmission and prospective vector controlR01AI110793 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI THOMAS, MATTHEW B · 2015 to 2018
$2.0M
Medical Research Council MR/R015600/1NIAID NIH HHS R01 AI110793Wellcome Trust
6 · The paper itself

Abstract

Despite concern that climate change could increase the human risk to malaria in certain areas, the temperature dependency of malaria transmission is poorly characterized. Here, we use a mechanistic model fitted to experimental data to describe how Plasmodium falciparum infection of the African malaria vector, Anopheles gambiae, is modulated by temperature, including its influences on parasite establishment, conversion efficiency through parasite developmental stages, parasite development rate, and overall vector competence. We use these data, together with estimates of the survival of infected blood-fed mosquitoes, to explore the theoretical influence of temperature on transmission in four locations in Kenya, considering recent conditions and future climate change. Results provide insights into factors limiting transmission in cooler environments and indicate that increases in malaria transmission due to climate warming in areas like the Kenyan Highlands, might be less than previously predicted.

Indexed as

AnophelesMalaria, FalciparumMosquito VectorsPlasmodium falciparumTemperatureAnimalsClimate ChangeFemaleHumansKenya

Identifiers

PMID38649361
PMCPMC11035611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.