Evidence map›Paper›PMID 38649192›Full record

ArticleCold Spring Harbor protocols2025

Laser Microsurgery in

Laura J Smithson, Thomas J Waller, Catherine A Collins

Abstract read
In one paragraph

Article in Cold Spring Harbor protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Immobilizing Second-InstarCold Spring Harbor protocols · 2025
    Article
  3. Study of Axonal Injury and Degeneration inCold Spring Harbor protocols · 2025
    Article
  4. Peripheral Nerve Crush inCold Spring Harbor protocols · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Laura J SmithsonDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.
Thomas J WallerDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.
Catherine A CollinsDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA cxc1215@case.edu.
University of Michigan–Ann Arbor · USCase Western Reserve University · US

Funding

Regenerative and Degenerative Responses to Axonal InjuryR01NS069844 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CADIGAN, KENNETH M, COLLINS, CATHERINE A · 2010 to 2024
$5.0M
Regenerative and degenerative responses to axonal injuryR56NS069844 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, CATHERINE A · 2020 to 2020
$546k
NINDS NIH HHS R01 NS069844NINDS NIH HHS R56 NS069844
6 · The paper itself

Abstract

Laser microsurgery is a robust method to ablate specific cells in the nervous system and probe the functional consequences of their loss in the animal. By introducing focal lesions to small locations in the animal, laser microsurgery also enables disruptions of specific connections within neuronal circuits and the study of how the nervous system responds to precise forms of damage (for instance, damage to specific axons or dendrites, which have been found to evoke different kinds of responses in neurons). The MicroPoint laser is a pulsed dye laser that can be mounted onto any standard microscope, hence is an affordable alternative to two-photon lasers for providing high powered focal ablations. This protocol describes how to use a MicroPoint laser ablation system to induce focal injuries in

Indexed as

DrosophilaLaser TherapyMicrosurgeryAnimalsLarva

Identifiers

PMID38649192
PMCPMC11701929
OpenAlexW4395083039

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.