ArticleJournal of clinical gastroenterology2025
Endoscopic Ultrasound-based Shear Wave Elastography for Detection of Advanced Liver Disease.
Article in Journal of clinical gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 9 citations in OpenAlex.
- Recent Development of Endo-hepatology.DEN open · 2027Review
- EUS-Guided Shear Wave Elastography in a Real-World Cohort: Diagnostic Accuracy and the Impact of Measurement Variability.Digestive diseases and sciences · 2026Article
- EUS-Guided Shear-Wave-Based Elastography: Current Evidence and the Emerging Role of Two-Dimensional Shear-Wave Elastography.Diagnostics (Basel, Switzerland) · 2026Review
- Intra-Observer Reproducibility of Endoscopic Ultrasound Point Shear-Wave Elastography: A 120-Patient Prospective Cohort Study.Medicina (Kaunas, Lithuania) · 2026Article
- Endoscopic ultrasound strain elastography in MASLD: Evaluation against transient elastography and non-invasive markers.Hepatology forum · 2026Article
- Advances in endoscopic ultrasound-guided shear wave elastography: A comprehensive review of its clinical applications.World journal of gastroenterology · 2025Review
- Role of Endoscopic Ultrasound in the Diagnosis and Management of Liver Diseases.Journal of clinical medicine · 2025Review
- Endoscopic ultrasound in the management of complications related to cirrhosis- recent evidence.World journal of gastrointestinal endoscopy · 2025Review
- Advances in Endo-Hepatology: The Role of Endoscopic Ultrasound in the Management of Portal Hypertension.Diagnostics (Basel, Switzerland) · 2025Review
- The evolution of diagnostic EUS: Milestones, technologies, and global contributions.Endoscopic ultrasoundReview
- EUS point shear-wave elastography: A novel approach for noninvasive liver fibrosis assessment.Endoscopic ultrasoundArticle
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
aimsEndoscopic ultrasound shear wave elastography (EUS-SWE) is a novel modality for liver stiffness measurement. The aims of this study are to evaluate the performance and reliability of EUS-SWE for detecting advanced liver disease in a prospective cohort.
methodsEUS-SWE measurements were prospectively obtained from patients undergoing EUS between August 2020 and March 2023. Liver stiffness measurements were compared between patients with and without advanced liver disease (ALD), defined as stage ≥3, to determine diagnostic accuracy for advanced fibrosis and portal hypertension. Logistic regression was performed to identify variables that impact the reliability of EUS-SWE readings. Select patients underwent paired magnetic resonance elastography (MRE) for liver fibrosis correlation.
resultsPatients with ALD demonstrated higher liver stiffness compared to healthy controls (left lobe: 17.6 vs. 12.7 kPa, P <0.001; median right lobe: 24.8 vs. 11.0 kPa, P <0.001). The area under the receiver operator characteristic (AUROC) for the detection of ALD was 0.73 and 0.80 for left and right lobe measurements, respectively. General anesthesia was associated with reliable EUS-SWE liver readings (odds ratio: 2.73, 95% CI: 1.07-7.39, P =0.040). Left lobe measurements correlated significantly with MRE with an increase of 0.11 kPa (95% CI: 0.05-0.17 kPA) for every 1 kPa increase on EUS-SWE. D.
conclusionsSWE is a promising technology that can readily be incorporated into standard EUS examinations for the assessment of ALD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.