Evidence map›Paper›PMID 38648420›Full record

ArticleJournal of medicinal chemistry2024

Discovery and Structure-Activity Relationships of 2,5-Dimethoxyphenylpiperidines as Selective Serotonin 5-HT

Emil M Ro Rsted, Anders A Jensen, Gints Smits, Karla Frydenvang, Jesper L Kristensen

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Discovery of Highly Selective 5-HTJournal of medicinal chemistry · 2025
    Article
  3. The Selective Serotonin 5‑HTACS pharmacology & translational science · 2025
    Article
  4. The Selective 5HTSynapse (New York, N.Y.) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emil M Ro RstedLophora, Charlottenlund, Copenhagen 2920, Denmark.ORCID 0000-0002-2783-6655
Anders A JensenLophora, Charlottenlund, Copenhagen 2920, Denmark.ORCID 0000-0002-7927-5052
Gints SmitsLatvian Institute of Organic Synthesis, Aizkraukles 21, Riga 1006, Latvia.ORCID 0000-0001-5044-4169
Karla FrydenvangDepartment of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, Copenhagen Ø 2100, Denmark.ORCID 0000-0002-5823-3478
Jesper L KristensenLophora, Charlottenlund, Copenhagen 2920, Denmark.ORCID 0000-0002-5613-1267

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Classical psychedelics such as psilocybin, lysergic acid diethylamide (LSD), and

Indexed as

PiperidinesReceptor, Serotonin, 5-HT2ASerotonin 5-HT2 Receptor AgonistsAnimalsDrug DiscoveryHumansLysergic Acid DiethylamideRatsStructure-Activity RelationshipLysergic Acid DiethylamidePiperidinesReceptor, Serotonin, 5-HT2ASerotonin 5-HT2 Receptor Agonists

Identifiers

PMID38648420
PMCPMC11089506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.