Evidence map›Paper›PMID 38648399›Full record

ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2024

Radiographic Fusion Outcomes for Trinity Cellular Based Allograft versus Local Bone in Posterolateral Lumbar Fusion.

Aatif Sayeed, Ali Jawad, Philip Zakko, Maximillian Lee, Daniel K Park

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Aatif SayeedFrom the Corewell Health William Beaumont University Hospital, Royal Oak, MI (Dr. Sayeed, Dr. Jawad, Dr. Zakko and Dr. Park); The Ohio State University School of Medicine, Columbus, OH (Dr. Lee).
Philip Zakko
Maximillian Lee
Daniel K Park
Lee University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCellular-based autograft (CBA) is being used in posterolateral lumbar arthrodesis as a fusion supplementation alternative.

objectiveTo assess radiographic fusion in patients undergoing posterolateral lumbar fusion with unilateral Trinity CBA compared with contralateral local bone autograft as an internal control.

methodsA single surgeon's practice database was interrogated for consecutive patients undergoing primary posterolateral lumbar fusion with Trinity from 2018 to 2021. Patients had Trinity applied unilaterally, with local bone autograft applied contralaterally. Fusion was assessed postoperatively by using CT after 9 months. Demographics and patient-reported outcome measures were collected preoperatively and up to 12 months postoperatively.

resultsThirty-nine patients were included. There were 81 attempted fusion levels. Overall fusion rate, defined as bony bridging on at least one side of a given level for all levels fused, was 85.2% of patients. No statistically significant difference was observed in fusion rates between CBA versus local bone (79.0% versus 76.54% of levels attempted, respectively, P = 0.3527). Oswestry Disability Index improved by 3 months (P = 0.0152) and was maintained. Two patients required revision for symptomatic nonunion.

conclusionsSimilar radiographic fusion rates were achieved with Trinity and local bone. Trinity is a viable alternative to local bone in posterolateral lumbar fusion.

Indexed as

Bone TransplantationLumbar VertebraeSpinal FusionAgedAllograftsAutograftsFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresRetrospective StudiesTransplantation, AutologousTreatment Outcome

Identifiers

PMID38648399
PMCPMC11037727
OpenAlexW4394993761

What OpenQuestion holds

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LicenceCC BY-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.