Evidence map›Paper›PMID 38648217›Full record

ArticlePLOS digital health2024

Automated reporting of cervical biopsies using artificial intelligence.

Mahnaz Mohammadi, Christina Fell, David Morrison, Sheeba Syed, Prakash Konanahalli, Sarah Bell, Gareth Bryson, Ognjen Arandjelović, David J Harrison, David Harris-Birtill

Open access · goldAbstract read
In one paragraph

Article in PLOS digital health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mahnaz MohammadiSchool of Computer Science, University of St Andrews, St Andrews, United Kingdom.ORCID https://orcid.org/0000-0002-3109-4324
Christina FellSchool of Computer Science, University of St Andrews, St Andrews, United Kingdom.ORCID https://orcid.org/0000-0003-0590-4132
David MorrisonSchool of Computer Science, University of St Andrews, St Andrews, United Kingdom.
Sheeba SyedDepartment of Pathology, Queen Elizabeth University Hospital, Glasgow, United Kingdom.
Prakash KonanahalliDepartment of Pathology, Queen Elizabeth University Hospital, Glasgow, United Kingdom.
Sarah BellDepartment of Pathology, Queen Elizabeth University Hospital, Glasgow, United Kingdom.
Gareth BrysonDepartment of Pathology, Queen Elizabeth University Hospital, Glasgow, United Kingdom.
Ognjen ArandjelovićSchool of Computer Science, University of St Andrews, St Andrews, United Kingdom.
David J HarrisonSchool of Medicine, University of St Andrews, United Kingdom.ORCID https://orcid.org/0000-0001-9041-9988
David Harris-BirtillSchool of Computer Science, University of St Andrews, St Andrews, United Kingdom.
University of St Andrews · GBQueen Elizabeth University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When detected at an early stage, the 5-year survival rate for people with invasive cervical cancer is 92%. Being aware of signs and symptoms of cervical cancer and early detection greatly improve the chances of successful treatment. We have developed an Artificial Intelligence (AI) algorithm, trained and evaluated on cervical biopsies for automated reporting of digital diagnostics. The aim is to increase overall efficiency of pathological diagnosis and to have the performance tuned to high sensitivity for malignant cases. Having a tool for triage/identifying cancer and high grade lesions may potentially reduce reporting time by identifying areas of interest in a slide for the pathologist and therefore improving efficiency. We trained and validated our algorithm on 1738 cervical WSIs with one WSI per patient. On the independent test set of 811 WSIs, we achieved 93.4% malignant sensitivity for classifying slides. Recognising a WSI, with our algorithm, takes approximately 1.5 minutes on the NVIDIA Tesla V100 GPU. Whole slide images of different formats (TIFF, iSyntax, and CZI) can be processed using this code, and it is easily extendable to other formats.

Identifiers

PMID38648217
PMCPMC11034655
OpenAlexW4394995825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.