Evidence map›Paper›PMID 38647973›Full record

ArticleBioresources and bioprocessing2024

Biotransformation of 2-keto-4-hydroxybutyrate via aldol condensation using an efficient and thermostable carboligase from Deinococcus radiodurans.

Yeon-Ju Jeong, Min-Ju Seo, Bong Hyun Sung, Jeong-Sun Kim, Soo-Jin Yeom

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioresources and bioprocessing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yeon-Ju Jeong *School of Biological Sciences and Biotechnology, Graduate School, Chonnam National University, Gwangju, Republic of Korea.
Min-Ju Seo *School of Biological Sciences and Technology, Chonnam National University, Gwangju, Republic of Korea.
Bong Hyun SungSynthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, Republic of Korea. bhsung@kribb.re.kr.
Jeong-Sun KimDepartment of Chemistry, Chonnam National University, Gwangju, 61186, Republic of Korea. jsunkim@chonnam.ac.kr.
Soo-Jin YeomSchool of Biological Sciences and Biotechnology, Graduate School, Chonnam National University, Gwangju, Republic of Korea. soojin258@jnu.ac.kr.ORCID http://orcid.org/0000-0001-7307-237X
Chonnam National University · KRKorea Research Institute of Bioscience and Biotechnology · KR

Funding

C1 Gas Refinery Program NRF-2018M3D3A1A01056181Enzyme engineering for next generation biorefinery NRF-2022M3J5A1056169Enzyme engineering for next generation biorefinery NRF-2022M3J5A1085239Korea Research Institute of Bioscience and the Biotechnology (KRIBB) Research Initiative Program KGM5402322
6 · The paper itself

Abstract

The bioconversion of 4-hydroxy-2-keto acid derivatives via aldol condensation of formaldehyde and pyruvate has received substantial attention as potential source of chemicals for production of amino acids, hydroxy carboxylic acids, and chiral aldehydes. We developed an environmentally friendly biocatalyst consisting of a novel thermostable class II pyruvate aldolase from Deinococcus radiodurans with maltose-binding protein (MBP-DrADL), which has specific activity of 46.3 µmol min

Indexed as

2-keto-4-hydroxybutyrateDeinococcus radioduransFormaldehydePyruvatePyruvate aldolase

Identifiers

PMID38647973
PMCPMC10992282
OpenAlexW4390914524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.