Evidence map›Paper›PMID 38647956›Full record

ReviewBioresources and bioprocessing2024

Enzyme engineering for functional lipids synthesis: recent advance and perspective.

Ailin Guan, Yue Hou, Run Yang, Jiufu Qin

Abstract readReview
In one paragraph

Review in Bioresources and bioprocessing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Synthetic Lipid Biology.Chemical reviews · 2025
    Review
  4. Recent insight into the advances and prospects of microbial lipases and their potential applications in industry.International microbiology : the official journal of the Spanish Society for Microbiology · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ailin GuanCollege of Biomass Science and Engineering, Sichuan University, Chengdu, 610065, China.
Yue HouCollege of Biomass Science and Engineering, Sichuan University, Chengdu, 610065, China.
Run YangCollege of Biomass Science and Engineering, Sichuan University, Chengdu, 610065, China.
Jiufu QinCollege of Biomass Science and Engineering, Sichuan University, Chengdu, 610065, China. jiufuq@scu.edu.cn.

Funding

Fundamental Research Funds for Central Universities of the Sichuan University YJ202308Natural Science Foundation of Sichuan Province 2023NSFSC0132
6 · The paper itself

Abstract

Functional lipids, primarily derived through the modification of natural lipids by various processes, are widely acknowledged for their potential to impart health benefits. In contrast to chemical methods for lipid modification, enzymatic catalysis offers distinct advantages, including high selectivity, mild operating conditions, and reduced byproduct formation. Nevertheless, enzymes face challenges in industrial applications, such as low activity, stability, and undesired selectivity. To address these challenges, protein engineering techniques have been implemented to enhance enzyme performance in functional lipid synthesis. This article aims to review recent advances in protein engineering, encompassing approaches from directed evolution to rational design, with the goal of improving the properties of lipid-modifying enzymes. Furthermore, the article explores the future prospects and challenges associated with enzyme-catalyzed functional lipid synthesis.

Indexed as

ActivityBiocatalysisFunctional lipidsProtein engineeringSelectivityStability

Identifiers

PMID38647956
PMCPMC10992173

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.