Evidence map›Paper›PMID 38647847›Full record

ReviewBioresources and bioprocessing2022

Biotechnological advances for improving natural pigment production: a state-of-the-art review.

Xiaomei Lyu, Yan Lyu, Hongwei Yu, WeiNing Chen, Lidan Ye, Ruijin Yang

Abstract readReview
In one paragraph

Review in Bioresources and bioprocessing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Natural Pigment Production byFoods (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Metabolic engineering ofBiodesign research · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Pigments from pathogenic bacteria: a comprehensive update on recent advances.World journal of microbiology & biotechnology · 2024
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaomei Lyu *School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.ORCID http://orcid.org/0000-0002-9008-6121
Yan Lyu *School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.
Hongwei YuInstitute of Bioengineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, People's Republic of China.
WeiNing ChenSchool of Chemical and Biomedical Engineering, College of Engineering, Nanyang Technological University, Singapore, 637459, Singapore.
Lidan YeInstitute of Bioengineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, People's Republic of China. yelidan@zju.edu.cn.ORCID http://orcid.org/0000-0002-6248-8457
Ruijin YangSchool of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China. yrj@jiangnan.edu.cn.

Funding

China Postdoctoral Science Foundation 2020M671339National Key Research and Development Program of China 2018YFA0901800National Natural Science Foundation of China 22108097Natural Science Foundation of Jiangsu Province BK20200616Natural Science Foundation of Zhejiang Province LZ20B060002
6 · The paper itself

Abstract

In current years, natural pigments are facing a fast-growing global market due to the increase of people's awareness of health and the discovery of novel pharmacological effects of various natural pigments, e.g., carotenoids, flavonoids, and curcuminoids. However, the traditional production approaches are source-dependent and generally subject to the low contents of target pigment compounds. In order to scale-up industrial production, many efforts have been devoted to increasing pigment production from natural producers, via development of both in vitro plant cell/tissue culture systems, as well as optimization of microbial cultivation approaches. Moreover, synthetic biology has opened the door for heterologous biosynthesis of pigments via design and re-construction of novel biological modules as well as biological systems in bio-platforms. In this review, the innovative methods and strategies for optimization and engineering of both native and heterologous producers of natural pigments are comprehensively summarized. Current progress in the production of several representative high-value natural pigments is also presented; and the remaining challenges and future perspectives are discussed.

Indexed as

Heterologous biosynthesisMetabolic engineeringMicrobial cultivationNatural pigmentsPlant cell/tissue culture

Identifiers

PMID38647847
PMCPMC10992905

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.