Evidence map›Paper›PMID 38647772›Full record

ArticleBioresources and bioprocessing2022

Efficient synthesis 1,4-cyclohexanedicarboxaldehyde by an engineered alcohol oxidase.

Yaqi Cheng, Wei Song, Xiulai Chen, Cong Gao, Jia Liu, Liang Guo, Meng Zhu, Liming Liu, Jing Wu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioresources and bioprocessing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yaqi ChengSchool of Life Sciences and Health Engineering, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.
Wei SongSchool of Life Sciences and Health Engineering, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.
Xiulai ChenState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Cong GaoState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Jia LiuState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Liang GuoState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Meng ZhuWuxi Acryl Technology Co., Ltd, Wuxi, 214122, China.
Liming LiuSchool of Life Sciences and Health Engineering, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.
Jing WuSchool of Life Sciences and Health Engineering, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China. wujing@jiangnan.edu.cn.
Jiangnan University · CNState Key Laboratory of Food Science and Technology · CN

Funding

Innovative Research Group Project of the National Natural Science Foundation of China 22178146National Key R & D Program of China 2021YFC2100100Natural Science Foundation of Jiangsu Province BK20200622
6 · The paper itself

Abstract

In this study, we selected and engineered a flavin adenine dinucleotide (FAD)-dependent alcohol oxidase (AOX) to produce 1,4-cyclohexanedicarboxaldehyde (CHDA), an initial raw material for spiral compounds, from 1,4-cyclohexanedimethanol (CHDM). First, the structure of alcohol oxidase from Arthrobacter cholorphenolicus (AcCO) was analyzed, and the mechanism of AcCO-catalyzed primary alcohol oxidation was elucidated, demonstrating that the energy barrier of the hydride (H

Indexed as

1,4-CyclohexanedicarboxaldehydeAlcohol oxidasePrimary alcohol oxidation reactionProtein engineering

Identifiers

PMID38647772
PMCPMC10991250
OpenAlexW4291189941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.