Kinetic modeling and process analysis for photo-production of β-carotene in Dunaliella salina.

Yimei Xi, Jiali Zhang, Fantao Kong, Jian Che, Zhanyou Chi

Open access · diamondAbstract read

In one paragraph

Article in Bioresources and bioprocessing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.4field-weighted citation impact, top 52% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

Fine-tuned regulation of photosynthetic performance via γ-aminobutyric acid (GABA) supply coupled with high initial cell density culture for economic starch production in microalgae.Bioresources and bioprocessing · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yimei XiKey Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education, China), School of Environmental Science and Technology, Dalian University of Technology, Dalian, 116024, China.

Jiali ZhangSchool of Mathematical Sciences, Dalian University of Technology, Dalian, 116024, China.

Fantao KongSchool of Bioengineering, Dalian University of Technology, Dalian, 116024, China. kongfantao@dlut.edu.cn.ORCID http://orcid.org/0000-0003-2847-2838

Jian CheSchool of Bioengineering, Dalian University of Technology, Dalian, 116024, China. jianche82@dlut.edu.cn.

Zhanyou ChiSchool of Bioengineering, Dalian University of Technology, Dalian, 116024, China.

Dalian University of Technology · CN

Funding

Fundamental Research Funds for Central Universities of the Central South University DUT21LK14Major and Special Program on Science and Technology Projects in Dalian City 2020ZD23SN009National Natural Science Foundation of China 31900221Natural Science Foundation of Liaoning Province 2020-MS-102

6 · The paper itself

Abstract

Dunaliella salina is a green microalga with the great potential to generate natural β-carotene. However, the corresponding mathematical models to guide optimized production of β-carotene in Dunaliella salina (D. salina) are not yet available. In this study, dynamic models were proposed to simulate effects of environmental factors on cell growth and β-carotene production in D. salina using online monitoring system. Moreover, the identification model of the parameter variables was established, and an adaptive particle swarm optimization algorithm based on parameter sensitivity analysis was constructed to solve the premature problem of particle swarm algorithm. The proposed kinetic model is characterized by high accuracy and predictability through experimental verification, which indicates its competence for future process design, control, and optimization. Based on the model established in this study, the optimal environmental factors for both β-carotene production and microalgae growth were identified. The approaches created are potentially useful for microalga Dunaliella salina cultivation and high-value β-carotene production.

Indexed as

Cultivation optimizationDunaliella salinaDynamic kinetic modelingEnvironmental factorsβ-Carotene production

Identifiers

PMID38647742

DOI10.1186/s40643-022-00495-6

PMCPMC10991233

OpenAlexW4225078467

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.