Evidence map›Paper›PMID 38647633›Full record

ArticlePhysical and engineering sciences in medicine2024

Comparison of commercial atlas-based automatic segmentation software for prostate radiotherapy treatment planning.

Diyana Afrina Hizam, Li Kuo Tan, Marniza Saad, Asyraf Muaadz, Ngie Min Ung

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Physical and engineering sciences in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Diyana Afrina HizamClinical Oncology Unit, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Li Kuo TanDepartment of Biomedical Imaging, Universiti Malaya, Kuala Lumpur, Malaysia. lktan@um.edu.my.
Marniza SaadClinical Oncology Unit, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Asyraf MuaadzDepartment of Clinical Oncology, University of Malaya Medical Centre, Kuala Lumpur, Malaysia.
Ngie Min UngClinical Oncology Unit, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia. nm_ung@um.edu.my.

Funding

Malaysia Ministry of Higher Education Fundamental Research Grant Scheme FRGS/1/2020/SKK03/UM/02/1
6 · The paper itself

Abstract

This study aims to assess the accuracy of automatic atlas-based contours for various key anatomical structures in prostate radiotherapy treatment planning. The evaluated structures include the bladder, rectum, prostate, seminal vesicles, femoral heads and penile bulb. CT images from 20 patients who underwent intensity-modulated radiotherapy were randomly chosen to create an atlas library. Atlas contours of the seven anatomical structures were generated using four software packages: ABAS, Eclipse, MIM, and RayStation. These contours were then compared to manual delineations performed by oncologists, which served as the ground truth. Evaluation metrics such as dice similarity coefficient (DSC), mean distance to agreement (MDA), and volume ratio (VR) were calculated to assess the accuracy of the contours. Additionally, the time taken by each software to generate the atlas contour was recorded. The mean DSC values for the bladder exhibited strong agreement (>0.8) with manual delineations for all software except for Eclipse and RayStation. Similarly, the femoral heads showed significant similarity between the atlas contours and ground truth across all software, with mean DSC values exceeding 0.9 and MDA values close to zero. On the other hand, the penile bulb displayed only moderate agreement with the ground truth, with mean DSC values ranging from 0.5 to 0.7 for all software. A similar trend was observed in the prostate atlas contours, except for MIM, which achieved a mean DSC of over 0.8. For the rectum, both ABAS and MIM atlases demonstrated strong agreement with the ground truth, resulting in mean DSC values of more than 0.8. Overall, MIM and ABAS outperformed Eclipse and RayStation in both DSC and MDA. These results indicate that the atlas-based segmentation employed in this study produces acceptable contours for the anatomical structures of interest in prostate radiotherapy treatment planning.

Indexed as

Prostatic NeoplasmsRadiotherapy Planning, Computer-AssistedSoftwareAutomationHumansImage Processing, Computer-AssistedMaleProstateRadiotherapy, Intensity-ModulatedTomography, X-Ray ComputedAtlas-based segmentationAutomatic contouringProstate radiotherapy

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.