ArticleHuman brain mapping2024
Comparative validation of automated presurgical tractography based on constrained spherical deconvolution and diffusion tensor imaging with direct electrical stimulation.
Article in Human brain mapping, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 10 citations in OpenAlex.
- Retrospective Comparative Analysis of Diffusion Tensor and Constrained Spherical Deconvolution Tractography Models in a Clinical Neurosurgical Navigation Platform.Neurologia medico-chirurgica · 2026Article
- Improving tractography in peri-lesional oedema using constrained spherical deconvolution in paediatric neurosurgery patients.Brain structure & function · 2026Article
- Cross-vendor reliability of functional and structural brain connectivity in a travelling cohort.Scientific reports · 2026Article
- Accuracy of corticospinal tract reconstruction: DTI-based deterministic versus probabilistic tractography with intraoperative validation.Frontiers in oncology · 2026Article
- Advanced diffusion MRI tractography for radiotherapy planning in pediatric brain tumors: A feasibility study.Physics and imaging in radiation oncology · 2026Article
- Does Fiber Orientation Distribution Really Outperform Diffusion Tensor Imaging-Based Tractography in the Clinic? A Diagnostic Test Accuracy Systematic Review and Meta-Analysis of Intraoperative Tractography.Neurosurgery practice · 2025Review
- The Role of Deep Cerebral Tracts in Predicting Postoperative Aphasia: An nTMS-Based Investigation of the Corticothalamic Fibers.Human brain mapping · 2025Article
- The scientific value of tractography: accuracy vs usefulness.Brain structure & function · 2025Article
- Due to difference in anatomical definitions, population variability and tractography methods, it will not be possible to standardize brain tractography for users, or will it?Brain structure & function · 2025Review
- Local response function estimation in spherical deconvolution for comprehensive tissue representation using diffusion MRI.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- A Virtual In Vivo Dissection and Analysis of Socioaffective Symptoms Related to Cerebellum-Midbrain Reward Circuitry in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Comparative validation of automated presurgical tractography based on constrained spherical deconvolution and diffusion tensor imaging with direct electrical stimulation.Human brain mapping · 2024Article
- A comparison of fMRI presurgical mapping techniques with intraoperative brain mapping-based validation.Imaging neuroscience (Cambridge, Mass.) · 2024Article
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAccurate presurgical brain mapping enables preoperative risk assessment and intraoperative guidance. This cross-sectional study investigated whether constrained spherical deconvolution (CSD) methods were more accurate than diffusion tensor imaging (DTI)-based methods for presurgical white matter mapping using intraoperative direct electrical stimulation (DES) as the ground truth.
methodsFive different tractography methods were compared (three DTI-based and two CSD-based) in 22 preoperative neurosurgical patients undergoing surgery with DES mapping. The corticospinal tract (CST, N = 20) and arcuate fasciculus (AF, N = 7) bundles were reconstructed, then minimum distances between tractograms and DES coordinates were compared between tractography methods. Receiver-operating characteristic (ROC) curves were used for both bundles. For the CST, binary agreement, linear modeling, and posthoc testing were used to compare tractography methods while correcting for relative lesion and bundle volumes.
resultsDistance measures between 154 positive (functional response, pDES) and negative (no response, nDES) coordinates, and 134 tractograms resulted in 860 data points. Higher agreement was found between pDES coordinates and CSD-based compared to DTI-based tractograms. ROC curves showed overall higher sensitivity at shorter distance cutoffs for CSD (8.5 mm) compared to DTI (14.5 mm). CSD-based CST tractograms showed significantly higher agreement with pDES, which was confirmed by linear modeling and posthoc tests (P
conclusionsCSD-based CST tractograms were more accurate than DTI-based ones when validated using DES-based assessment of motor and sensory function. This demonstrates the potential benefits of structural mapping using CSD in clinical practice.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.