Evidence map›Paper›PMID 38646648›Full record

ReviewTheranostics2024

Theranostics - a sure cure for cancer after 100 years?

Yangmeihui Song, Jianhua Zou, E Alejandro Castellanos, Naomi Matsuura, John A Ronald, Adam Shuhendler, Wolfgang A Weber, Assaf A Gilad, Cristina Müller, Timothy H Witney and 1 more

Abstract readReview
In one paragraph

Review in Theranostics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Targeted Radionuclide Therapy: Current Landscape and Combination Approaches to Improve Oncology Outcomes.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
    Review
  3. Linking In Vivo Imaging to Therapeutic Outcome withInternational journal of molecular sciences · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Safety and efficacy of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. The Evolution of Fluorescein into A Potential Theranostic Tool.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  17. Article
  18. Review
  19. Current Advances in Nanocarriers for Cancer Therapy.International journal of nanomedicine · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yangmeihui SongDepartment of Nuclear Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, 81675, Germany.
Jianhua ZouDepartments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, 119074, Singapore.
E Alejandro CastellanosDepartment of Biomedical Engineering, Michigan State University, East Lansing, MI, USA.
Naomi MatsuuraInstitute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
John A RonaldImaging Laboratories, Department of Medical Biophysics, Robarts Research Institute, University of Western Ontario, London, ON, Canada.
Adam ShuhendlerUniversity of Ottawa Heart Institute, Ottawa, ON, Canada.
Wolfgang A WeberDepartment of Nuclear Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, 81675, Germany.
Assaf A GiladDepartment of Chemical Engineering and Materials Sciences, Michigan State University, East Lansing, MI, USA.
Cristina MüllerCenter for Radiopharmaceutical Sciences, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland.
Timothy H WitneySchool of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.
Xiaoyuan ChenDepartments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, 119074, Singapore.

Funding

Wellcome Trust 220221
6 · The paper itself

Abstract

Cancer has remained a formidable challenge in medicine and has claimed an enormous number of lives worldwide. Theranostics, combining diagnostic methods with personalized therapeutic approaches, shows huge potential to advance the battle against cancer. This review aims to provide an overview of theranostics in oncology: exploring its history, current advances, challenges, and prospects. We present the fundamental evolution of theranostics from radiotherapeutics, cellular therapeutics, and nanotherapeutics, showcasing critical milestones in the last decade. From the early concept of targeted drug delivery to the emergence of personalized medicine, theranostics has benefited from advances in imaging technologies, molecular biology, and nanomedicine. Furthermore, we emphasize pertinent illustrations showcasing that revolutionary strategies in cancer management enhance diagnostic accuracy and provide targeted therapies customized for individual patients, thereby facilitating the implementation of personalized medicine. Finally, we describe future perspectives on current challenges, emerging topics, and advances in the field.

Indexed as

NeoplasmsPrecision MedicineTheranostic NanomedicineAnimalsDrug Delivery SystemsHistory, 20th CenturyHistory, 21st CenturyHumansNanomedicinecancernanotheranosticspersonalized medicineradiotheranosticssynthetic biology

Identifiers

PMID38646648
PMCPMC11024861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.