Evidence map›Paper›PMID 38646641›Full record

ArticleTheranostics2024

Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healing.

Ran Liu, Yu-Rui Jiao, Mei Huang, Nan-Yu Zou, Chen He, Min Huang, Kai-Xuan Chen, Wen-Zhen He, Ling Liu, Yu-Chen Sun and 7 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. The Important Role of Polycystin in the Skeletal System.Calcified tissue international · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. A Novel Deer Antler-Inspired Bone Graft Triggers Rapid Bone Regeneration.Advanced materials (Deerfield Beach, Fla.) · 2025
    Article
  11. Progress on the mechanism of Polycystin-1 in bone remodeling.Frontiers in cell and developmental biology · 2025
    Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Ran LiuDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, China.
Yu-Rui JiaoDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, China.
Mei HuangDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, China.
Nan-Yu ZouDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, China.
Chen HeDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, China.
Min HuangDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, China.
Kai-Xuan ChenDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, China.
Wen-Zhen HeDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, China.
Ling LiuDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, China.
Yu-Chen SunDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, China.
Zhu-Ying XiaDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, China.
L Darryl QuarlesDepartment of Medicine, University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
Hai-Lin YangDepartment of Orthopaedics, The Second Affiliated Hospital of Fuyang Normal University, Fuyang, Anhui, 236000, China.
Wei-Shan WangDepartment of Orthopaedics, The First Affiliated Hospital of Shihezi University, Shihezi 832061, China.
Zhou-Sheng XiaoDepartment of Medicine, University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
Xiang-Hang LuoDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, China.
Chang-Jun LiDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410008, China.
Central South University · CNXiangya Hospital Central South University · CNUniversity of Tennessee Health Science Center · USFirst Affiliated Hospital of Shihezi University Medical College · CNFuyang Normal University · CN

Funding

Skeletal Functions of Polycystins and TAZR01AR071930 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI XIAO, ZHOUSHENG · 2018 to 2022
$1.6M
Optimization of Novel Small Molecules to Antagonize FGF-23R01DK121132 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI XIAO, ZHOUSHENG · 2019 to 2023
$1.5M
Polycystins/TAZ as a novel therapeutic target to treat osteoporosisR61AR073518 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI QUARLES, L DARRYL · 2018 to 2019
$752k
NIAMS NIH HHS R01 AR071930NIAMS NIH HHS R61 AR073518NIDDK NIH HHS R01 DK121132
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adaptor Proteins, Signal TransducingCell DifferentiationChondrocytesFracture HealingOsteogenesisStem CellsTRPP Cation ChannelsAnimalsChondrogenesisDisease Models, AnimalMaleMiceMice, KnockoutOsteoblastsPeriosteumAdaptor Proteins, Signal TransducingTRPP Cation ChannelsWwtr1 protein, mouseFracture healingMechanical stressPeriosteal Stem/Progenitor CellsPolycystin-1

Identifiers

PMID38646641
PMCPMC11024844
OpenAlexW4394735160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.