ArticleCureus2024
In Vitro Comparison to Evaluate Metal Ion Release: Nickel-Titanium vs. Titanium-Molybdenum Orthodontic Archwires.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 8 citations in OpenAlex.
- Nickel Ion Release in Nickel-Containing Orthodontics Archwires: A Narrative Review of In Vitro and In Vivo Studies.Dentistry journal · 2025Review
- Orthodontic Alloy Wires and Their Hypoallergenic Alternatives: Metal Ions Release in pH 6.6 and pH 5.5 Artificial Saliva.Materials (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background When metals used in orthodontic materials are exposed to the oral environment, teeth, and gingivae over an extended period of time, they may gradually deteriorate. As a result, the patient is exposed to higher concentrations of metals and metal ions than what they would be exposed to through food and other sources. The goal of the current in vitro experiment was to evaluate and contrast the metal ion release from orthodontic archwires made of titanium-molybdenum alloy (TMA) and nickel-titanium (NiTi). Methods For 90 days, 20 orthodontic archwires in each group were immersed in 50 milliliters of simulated saliva using different containers. Atomic Absorption Spectrometry (AAS) (Shimadzu Corporation, Kyoto, Japan) was used to assess and compare metal ion emission. The unit of measurement is parts per million (PPM). Results The findings indicated that the discharge of nickel metal from the NiTi archwire (Group A) was much higher than that from the TMA archwire (Group B), with a statistical significance level of p < 0.001. It was discovered that Group B's release of titanium was statistically significantly (p < 0.05) higher than Group A's titanium release, which did not include the release of any other metals. Conclusion The study findings indicated that the amounts of metal ions released from the orthodontic archwires made of titanium molybdenum and nickel-titanium alloy were within safety limits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.