Evidence map›Paper›PMID 38645776›Full record

ArticleFrontiers in chemistry2024

Exploring theophylline-1,2,4-triazole tethered

Sadaf Saeed, Irum Shahzadi, Ameer Fawad Zahoor, Aamal A Al-Mutairi, Shagufta Kamal, Shah Faisal, Ali Irfan, Sami A Al-Hussain, Muhammed Tilahun Muhammed, Magdi E A Zaki

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In one paragraph

Article in Frontiers in chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Sadaf SaeedDepartment of Chemistry, Government College University Faisalabad, Faisalabad, Pakistan.
Irum ShahzadiDepartment of Chemistry, Government College University Faisalabad, Faisalabad, Pakistan.
Ameer Fawad ZahoorDepartment of Chemistry, Government College University Faisalabad, Faisalabad, Pakistan.
Aamal A Al-MutairiDepartment of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Shagufta KamalDepartment of Biochemistry, Government College University Faisalabad, Faisalabad, Pakistan.
Shah FaisalDepartment of Chemistry, Islamia College University Peshawar, Peshawar, Pakistan.
Ali IrfanDepartment of Chemistry, Government College University Faisalabad, Faisalabad, Pakistan.
Sami A Al-HussainDepartment of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Muhammed Tilahun MuhammedDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Suleyman Demirel University, Isparta, Türkiye.
Magdi E A ZakiDepartment of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Government College University, Faisalabad · PKImam Mohammad ibn Saud Islamic University · SAIslamia College University · PKSuleyman Demirel University · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Theophylline, a nitrogen-containing heterocycle, serves as a promising focal point for medicinal researchers aiming to create derivatives with diverse pharmacological applications. In this work, we present an improved synthetic method for a range of theophylline-1,2,4-triazole-S-linked N-phenyl acetamides (4a‒g) utilizing ultrasound-assisted synthetic approach. The objective was to assess the effectiveness of synthesized theophylline-1,2,4-triazoles (4a‒g) as inhibitors of HCV serine protease and as antibacterial agents against

Indexed as

antibacterial agentsDFT studyhigh yieldsmolecular dockingSARserine protease inhibitorstheophylline-1,2,4-triazolesultrasonic assisted approach

Identifiers

PMID38645776
PMCPMC11026557
OpenAlexW4393985050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.