Evidence map›Paper›PMID 38645466›Full record

ArticleGastro hep advances2024

Esophageal Symptoms and Lumbosacral Back Pain.

Ravinder K Mittal, Charlie Le, Melissa Ledgerwood, Da Kyung Jung, Vignesh Gandu, Ali Zifan

Open access · goldAbstract read
In one paragraph

Article in Gastro hep advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ravinder K MittalDivision of Gastroenterology, Department of Medicine University of California San Diego, San Diego, California.
Charlie LeDivision of Gastroenterology, Department of Medicine University of California San Diego, San Diego, California.
Melissa LedgerwoodDivision of Gastroenterology, Department of Medicine University of California San Diego, San Diego, California.
Da Kyung JungDivision of Gastroenterology, Department of Medicine University of California San Diego, San Diego, California.
Vignesh GanduDivision of Gastroenterology, Department of Medicine University of California San Diego, San Diego, California.
Ali ZifanDivision of Gastroenterology, Department of Medicine University of California San Diego, San Diego, California.
University of San Diego · US

Funding

Novel Electrical Impedance Methodology to Understand Functional DysphagiaR01DK109376 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MITTAL, RAVINDER K. · 2016 to 2020
$2.5M
Novel Electrical Impedance Methodology to Understand Functional DysphagiaR56DK109376 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MITTAL, RAVINDER K., ZIFAN, ALI · 2023 to 2023
$682k
NIDDK NIH HHS R01 DK109376NIDDK NIH HHS R56 DK109376
6 · The paper itself

Abstract

BACKGROUND AND

aimsEsophageal symptoms, that is, heartburn, regurgitation, dysphagia, and chest pain are common in the general population. Also common are symptoms of back pain related to pathology in the lumbosacral spine. The right crus of the diaphragm that forms the esophageal hiatus, originates from lumbar spine, may be affected by lumbar spine pathology resulting in esophageal symptoms. We studied whether there was an association between esophageal symptoms and spine symptoms.

methodsTwo patient groups of 150 each were investigated: group 1 (ES); patients referred to the esophageal manometry study for assessment of esophageal symptoms, group 2 (SC); patients undergoing screening colonoscopy (control group). Both groups completed standardized questionnaires assessing esophageal and spine symptoms.

resultsBack pain was reported by 74% of patients in the ES group as compared to 55% of patients in the SC group. Thirty percent of patients in the SC group reported one or more esophageal symptoms and these patients were regrouped with the ES group, resulting in 2 groups, ES1 and SC1, with and without esophageal symptoms, respectively. The ES1 group was 3.3 times more likely to experience back pain compared to the SC1 group (95% confidence interval: 1.95-5.46). Thoracolumbar was the most common site of pain in both groups. Pain score was greater for the group with esophageal symptoms compared to controls. Narcotic intake for most patients in the ES1 group was for back pain.

conclusionA strong association between esophageal symptoms and thoracolumbar back pain raises the possibility that structural and functional changes in the esophageal hiatus muscles related to thoracolumbar spine pathology lead to esophageal dysmotility and symptoms.

Indexed as

Esophageal HiatusEsophageal SymptomsThoracolumbar Back Pain

Identifiers

PMID38645466
PMCPMC11027073
OpenAlexW4388871781

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.