Evidence map›Paper›PMID 38645214›Full record

ArticlebioRxiv : the preprint server for biology2024

Resource: A Curated Database of Brain-Related Functional Gene Sets (Brain.GMT).

Megan H Hagenauer, Yusra Sannah, Elaine K Hebda-Bauer, Cosette Rhoads, Angela M O'Connor, Stanley J Watson, Huda Akil

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Megan H HagenauerMichigan Neuroscience Institute, University of Michigan, Ann Arbor; MI 48109, USA.ORCID 0000-0002-3715-9475
Yusra SannahMichigan Neuroscience Institute, University of Michigan, Ann Arbor; MI 48109, USA.ORCID 0009-0002-1120-0473
Elaine K Hebda-BauerMichigan Neuroscience Institute, University of Michigan, Ann Arbor; MI 48109, USA.ORCID 0000-0002-0043-3944
Cosette RhoadsMichigan Neuroscience Institute, University of Michigan, Ann Arbor; MI 48109, USA.ORCID 0009-0007-8670-7814
Angela M O'ConnorMichigan Neuroscience Institute, University of Michigan, Ann Arbor; MI 48109, USA.ORCID 0000-0002-0053-1835
Stanley J WatsonMichigan Neuroscience Institute, University of Michigan, Ann Arbor; MI 48109, USA.ORCID 0000-0003-4980-5523
Huda AkilMichigan Neuroscience Institute, University of Michigan, Ann Arbor; MI 48109, USA.ORCID 0000-0003-0623-1056

Funding

Investigating the role of Bmp4 in glial subtype specification and temperamentU01DA043098 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUDA AKIL, Jun Li · 2017 to 2026
$6.9M
NIDA NIH HHS U01 DA043098
6 · The paper itself

Abstract

Transcriptional profiling has become a common tool for investigating the nervous system. During analysis, differential expression results are often compared to functional ontology databases, which contain curated gene sets representing well-studied pathways. This dependence can cause neuroscience studies to be interpreted in terms of functional pathways documented in better studied tissues (

Indexed as

Central Nervous SystemDifferential Expression AnalysisFrontal CortexGene Set Enrichment Analysis (GSEA)GenomicsHippocampusMicroarrayNucleus AccumbensRNA-SeqTranscriptional Profiling

Identifiers

PMID38645214
PMCPMC11030436

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.