Evidence map›Paper›PMID 38645138›Full record

ArticlebioRxiv : the preprint server for biology2024

Glia-derived secretory fatty acid binding protein Obp44a regulates lipid storage and efflux in the developing

Jun Yin, Hsueh-Ling Chen, Anna Grigsby-Brown, Yi He, Myriam L Cotten, Jacob Short, Aidan Dermady, Jingce Lei, Mary Gibbs, Ethan S Cheng and 11 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 7 institutions in 1 country.

Jun YinDendrite Morphogenesis and Plasticity Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
Hsueh-Ling ChenDendrite Morphogenesis and Plasticity Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
Anna Grigsby-BrownDendrite Morphogenesis and Plasticity Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
Yi HeFermentation Facility, Biochemistry and Biophysics Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Myriam L CottenDepartment of Biochemistry and Biophysics, Oregon State University, Corvallis, OR.
Jacob ShortDendrite Morphogenesis and Plasticity Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
Aidan DermadyDendrite Morphogenesis and Plasticity Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
Jingce LeiDendrite Morphogenesis and Plasticity Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
Mary GibbsDendrite Morphogenesis and Plasticity Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
Ethan S ChengDendrite Morphogenesis and Plasticity Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
Dean ZhangDendrite Morphogenesis and Plasticity Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
Caixia LongDendrite Morphogenesis and Plasticity Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
Lele XuAdvanced Science Research Center, The City University of New York, New York, NY.
Tiffany ZhongNeuroscience Program, Princeton University, Princeton, NJ.
Rinat AbzalimovAdvanced Science Research Center, The City University of New York, New York, NY.
Mariam HaiderDepartment of Cell and Developmental Biology, Vanderbilt Brain Institute, Center for Structural Biology, Vanderbilt Kennedy Center, Vanderbilt University, Nashville, TN.
Rong SunDepartment of Cell and Developmental Biology, Vanderbilt Brain Institute, Center for Structural Biology, Vanderbilt Kennedy Center, Vanderbilt University, Nashville, TN.
Ye HeAdvanced Science Research Center, The City University of New York, New York, NY.
Qiangjun ZhouDepartment of Cell and Developmental Biology, Vanderbilt Brain Institute, Center for Structural Biology, Vanderbilt Kennedy Center, Vanderbilt University, Nashville, TN.ORCID 0000-0003-1789-9588
Nico TjandraLaboratory of Molecular Biophysics, Biochemistry and Biophysics Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Quan YuanDendrite Morphogenesis and Plasticity Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.ORCID 0000-0002-0676-2079
National Institute of Neurological Disorders and Stroke · USThe Graduate Center, CUNY · USVanderbilt University · USNational Heart Lung and Blood Institute · USNational Institutes of Health · USOregon State University · USPrinceton University · US

Funding

Study dendrite morphogenesis and activity-dependent plasticity using DrosophilaZIANS003137 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI YUAN, QUAN · 2013 to 2025
$24.9M
Synaptic nanostructure and dysfunction in neurodevelopmental disordersR01MH132918 · NIMH · VANDERBILT UNIVERSITY · PI Qiangjun Zhou · 2024 to 2026
$1.8M
Mechanical regulation of intestine stem cell-mediated tissue homeostasis in DrosophilaR01DK136013 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Patrick Emery · 2023 to 2026
$1.5M
Molecular Mechanism and Regulation of Asynchronous ReleaseR00MH113764 · NIMH · VANDERBILT UNIVERSITY · PI ZHOU, QIANGJUN · 2020 to 2022
$719k
Intramural NIH HHS ZIA NS003137NIDDK NIH HHS R01 DK136013NIMH NIH HHS R00 MH113764NIMH NIH HHS R01 MH132918
6 · The paper itself

Abstract

Glia derived secretory factors play diverse roles in supporting the development, physiology, and stress responses of the central nervous system (CNS). Through transcriptomics and imaging analyses, we have identified Obp44a as one of the most abundantly produced secretory proteins from

Identifiers

PMID38645138
PMCPMC11030299
OpenAlexW4394725595

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.