Evidence map›Paper›PMID 38645122›Full record

ArticlebioRxiv : the preprint server for biology2024

Machine Learned Classification of Ligand Intrinsic Activities at Human

Myongin Oh, Maximilian Shen, Ruibin Liu, Lidiya Stavitskaya, Jana Shen

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Myongin OhDivision of Applied Regulatory Science, Office of Clinical Pharmacology, Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD 20993, United States.ORCID 0000-0003-1145-5142
Maximilian ShenDepartment of Electrical and Computer Engineering, University of Maryland, College Park, MD.ORCID 0009-0006-7435-9034
Ruibin LiuDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, United States.ORCID 0000-0001-8395-9353
Lidiya StavitskayaDivision of Applied Regulatory Science, Office of Clinical Pharmacology, Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD 20993, United States.ORCID 0000-0002-6307-2314
Jana ShenDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, United States.ORCID 0000-0002-3234-0769
University of Maryland, Baltimore · USUnited States Food and Drug Administration · USUniversity of Maryland, College Park · US

Funding

Molecular mechanisms of proton-coupled dynamic processes in biologyR35GM148261 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI Jana Shen · 2023 to 2026
$1.5M
A Multi-pronged Computational Approach to Advance Kinase Drug DiscoveryR01CA256557 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI SHEN, JANA · 2021 to 2024
$1.4M
NCI NIH HHS R01 CA256557NIGMS NIH HHS R35 GM148261
6 · The paper itself

Abstract

Opioids are small-molecule agonists of

Indexed as

agonismartificial intelligencechemical structureopioidSMILE

Identifiers

PMID38645122
PMCPMC11030315
OpenAlexW4394694642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.