Evidence map›Paper›PMID 38645007›Full record

ArticlebioRxiv : the preprint server for biology2024

Lateral cell polarization drives organization of epithelia in sea anemone embryos and embryonic cell aggregates.

Tavus Atajanova, Emily Minju Kang, Anna Postnikova, Alivia Lee Price, Sophia Doerr, Michael Du, Alicia Ugenti, Katerina Ragkousi

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tavus AtajanovaDepartment of Biology, Amherst College, Amherst, MA 01002, USA.
Emily Minju KangDepartment of Biology, Amherst College, Amherst, MA 01002, USA.
Anna PostnikovaDepartment of Biology, Amherst College, Amherst, MA 01002, USA.
Alivia Lee PriceDepartment of Biology, Amherst College, Amherst, MA 01002, USA.
Sophia DoerrDepartment of Biology, Amherst College, Amherst, MA 01002, USA.
Michael DuDepartment of Biology, Amherst College, Amherst, MA 01002, USA.
Alicia UgentiDepartment of Biology, Amherst College, Amherst, MA 01002, USA.
Katerina RagkousiDepartment of Biology, Amherst College, Amherst, MA 01002, USA.ORCID 0000-0001-9383-225X
Amherst College · USOregon Research Institute · US

Funding

Cell cycle regulation of polarity proteins in proliferating epitheliaR15GM141979 · NIGMS · AMHERST COLLEGE · PI RAGKOUSI, KATERINA · 2021 to 2023
$553k
NIGMS NIH HHS R15 GM141979
6 · The paper itself

Abstract

One of the first organizing processes during animal development is the assembly of embryonic cells into epithelia. In certain animals, including Hydra and sea anemones, epithelia also emerge when cells from dissociated tissues are aggregated back together. Although cell adhesion is required to keep cells together, it is not clear whether cell polarization plays a role as epithelia emerge from disordered aggregates. Here, we demonstrate that lateral cell polarization is essential for epithelial organization in both embryos and aggregates of the sea anemone

Identifiers

PMID38645007
PMCPMC11030385
OpenAlexW4394675448

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.