Evidence map›Paper›PMID 38644992›Full record

ArticlebioRxiv : the preprint server for biology2024

Assembly of the Bacterial Ribosome with Circularly Permuted rRNA.

Xiyu Dong, Kai Sheng, Luca F R Gebert, Sriram Aiyer, Ian J MacRae, Dmitry Lyumkis, James R Williamson

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiyu DongDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0002-1766-3324
Kai ShengDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0001-9394-2256
Luca F R GebertDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0002-1830-119X
Sriram AiyerLaboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.ORCID 0000-0001-6436-0521
Ian J MacRaeDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0002-5112-0294
Dmitry LyumkisLaboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.ORCID 0000-0002-8124-7472
James R WilliamsonDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0002-8772-468X
Scripps Research Institute · USSalk Institute for Biological Studies · US

Funding

Structural Biology CoreU54AI170855 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI Karen A Kirby · 2022 to 2026
$36.7M
Structural and Mechanistic basis for RNA SilencingR35GM127090 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI IAN JOHN MACRAE · 2018 to 2026
$5.6M
Dynamics of the Bacterial Ribosome and Proteome (Equipment Supplement)R35GM136412 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI James R Williamson · 2020 to 2026
$4.9M
NIAID NIH HHS U54 AI170855NIGMS NIH HHS R35 GM127090NIGMS NIH HHS R35 GM136412
6 · The paper itself

Abstract

Co-transcriptional assembly is an integral feature of the formation of RNA-protein complexes that mediate translation. For ribosome synthesis, prior studies have indicated that the strict order of transcription of rRNA domains may not be obligatory during bacterial ribosome biogenesis, since a series of circularly permuted rRNAs are viable. In this work, we report the insights into assembly of the bacterial ribosome large subunit (LSU) based on cryo-EM density maps of intermediates that accumulate during

Identifiers

PMID38644992
PMCPMC11030442
OpenAlexW4394723682

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.