Evidence map›Paper›PMID 38644934›Full record

ArticlePhysics and imaging in radiation oncology2024

A deep learning based dynamic arc radiotherapy photon dose engine trained on Monte Carlo dose distributions.

Marnix Witte, Jan-Jakob Sonke

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marnix WitteDepartment of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Jan-Jakob SonkeDepartment of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Despite hardware acceleration, state-of-the-art Monte Carlo (MC) dose engines require considerable computation time to reduce stochastic noise. We developed a deep learning (DL) based dose engine reaching high accuracy at strongly reduced computation times. Materials and methods: Radiotherapy treatment plans and computed tomography scans were collected for 350 treatments in a variety of tumor sites. Dose distributions were computed using a MC dose engine for Results: DL dose evaluation was on average 82 times faster than MC computation at a 1 % accuracy setting. In voxels receiving at least 10 % of the maximum dose the overall global gamma pass rate using a 2 % and 2 mm criterion was 99.6 %, while mean local gamma values were accurate within 2 %. In the high dose region over 50 % of maximum the mean local gamma approached a 1 % accuracy. Conclusions: A DL based dose engine was implemented, able to accurately reproduce MC computed dynamic arc radiotherapy dose distributions at high speed.

Indexed as

Deep learningDose engineRadiotherapy

Identifiers

PMID38644934
PMCPMC11031817

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.