Evidence map›Paper›PMID 38644848›Full record

ArticleHeliyon2024

Improving radiomic modeling for the identification of symptomatic carotid atherosclerotic plaques using deep learning-based 3D super-resolution CT angiography.

Lingjie Wang, Tiedan Guo, Li Wang, Wentao Yang, Jingying Wang, Jianlong Nie, Jingjing Cui, Pengbo Jiang, Junlin Li, Hua Zhang

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lingjie WangDepartment of Medical Imaging, First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, 030001, China.
Tiedan GuoDepartment of Medical Imaging, First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, 030001, China.
Li WangDepartment of Medical Imaging, First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, 030001, China.
Wentao YangBasic Medical College, Shanxi Medical University, Taiyuan, Shanxi Province, 030001, China.
Jingying WangDepartment of Endemic Disease Prevention and Control, Shanxi Province Disease Prevention and Control Center, Shanxi Province, 030001, China.
Jianlong NieShanghai United Imaging Intelligence, Co., Ltd., Shanghai City, 200030, China.
Jingjing CuiShanghai United Imaging Intelligence, Co., Ltd., Shanghai City, 200030, China.
Pengbo JiangShanghai United Imaging Intelligence, Co., Ltd., Shanghai City, 200030, China.
Junlin LiDepartment of Imaging Medicine, Inner Mongolia Autonomous Region People's Hospital, Hohhot, 010017, China.
Hua ZhangDepartment of Medical Imaging, First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, 030001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rationale and objectives: Radiomic models based on normal-resolution (NR) computed tomography angiography (CTA) images can fail to distinguish between symptomatic and asymptomatic carotid atherosclerotic plaques. This study aimed to explore the effectiveness of a deep learning-based three-dimensional super-resolution (SR) CTA radiomic model for improved identification of symptomatic carotid atherosclerotic plaques. Materials and methods: A total of 193 patients with carotid atherosclerotic plaques were retrospectively enrolled and allocated into either a symptomatic (n = 123) or an asymptomatic (n = 70) groups. SR CTA images were derived from NR CTA images using deep learning-based three-dimensional SR technology. Handcrafted radiomic features were extracted from both the SR and NR CTA images and three risk models were developed based on manually measured quantitative CTA characteristics and NR and SR radiomic features. Model performances were assessed via receiver operating characteristic, calibration, and decision curve analyses. Results: The SR model exhibited the optimal performance (area under the curve [AUC] 0.820, accuracy 0.802, sensitivity 0.854, F1 score 0.847) in the testing cohort, outperforming the other two models. The calibration curve analyses and Hosmer-Lemeshow test demonstrated that the SR model exhibited the best goodness of fit, and decision curve analysis revealed that SR model had the highest clinical value and potential patient benefits. Conclusions: Deep learning-based three-dimensional SR technology could improve the CTA-based radiomic models in identifying symptomatic carotid plaques, potentially providing more accurate and valuable information to guide clinical decision-making to reduce the risk of ischemic stroke.

Indexed as

Carotid plaquesComputed tomography angiographyDeep learningRadiomicsSuper-resolution

Identifiers

PMID38644848
PMCPMC11033096

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.