Evidence map›Paper›PMID 38644661›Full record

ArticleJournal of materials chemistry. B2024

Laser-assisted surface alloying of titanium with silver to enhance antibacterial and bone-cell mineralization properties of orthopedic implants.

Sotoudeh Sedaghat, Akshay Krishnakumar, Vidhya Selvamani, James P Barnard, Sina Nejati, Haiyan Wang, David A Detwiler, Mohamed N Seleem, Rahim Rahimi

Open access · hybridAbstract read
In one paragraph

Article in Journal of materials chemistry. B, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sotoudeh SedaghatSchool of Materials Engineering, Purdue University, West Lafayette, IN 47907, USA. rrahimi@purdue.edu.ORCID 0000-0001-6243-5665
Akshay KrishnakumarBirck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA.
Vidhya SelvamaniSchool of Materials Engineering, Purdue University, West Lafayette, IN 47907, USA. rrahimi@purdue.edu.ORCID 0000-0001-8122-9648
James P BarnardSchool of Materials Engineering, Purdue University, West Lafayette, IN 47907, USA. rrahimi@purdue.edu.ORCID 0000-0002-7570-952X
Sina NejatiSchool of Materials Engineering, Purdue University, West Lafayette, IN 47907, USA. rrahimi@purdue.edu.ORCID 0000-0003-4294-7262
Haiyan WangSchool of Materials Engineering, Purdue University, West Lafayette, IN 47907, USA. rrahimi@purdue.edu.ORCID 0000-0002-7397-1209
David A DetwilerBirck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA.
Mohamed N SeleemDepartment of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
Rahim RahimiSchool of Materials Engineering, Purdue University, West Lafayette, IN 47907, USA. rrahimi@purdue.edu.ORCID 0000-0001-5302-782X
Purdue University West Lafayette · USVirginia Tech · US

Funding

Swallowable smart capsule for targeted gastrointestinal microbiome samplingR21DK128715 · NIDDK · PURDUE UNIVERSITY · PI CAMPBELL, WAYNE W, CROSS, TZU-WEN LIU · 2022 to 2023
$407k
NIDDK NIH HHS R21 DK128715
6 · The paper itself

Abstract

Orthopedic device-related infection (ODRI) poses a significant threat to patients with titanium-based implants. The challenge lies in developing antibacterial surfaces that preserve the bulk mechanical properties of titanium implants while exhibiting characteristics similar to bone tissue. In response, we present a two-step approach: silver nanoparticle (AgNP) coating followed by selective laser-assisted surface alloying on commonly used titanium alumina vanadium (TiAl6V4) implant surfaces. This process imparts antibacterial properties without compromising the bulk mechanical characteristics of the titanium alloy. Systematic optimization of laser beam power (8-40 W) resulted in an optimized surface (32 W) with uniform TiAg alloy formation. This surface displayed a distinctive hierarchical mesoporous textured surface, featuring cauliflower-like nanostructures measuring between 5-10 nm uniformly covering spatial line periods of 25 μm while demonstrating homogenous elemental distribution of silver throughout the laser processed surface. The optimized laser processed surface exhibited prolonged superhydrophilicity (40 days) and antibacterial efficacy (12 days) against

Indexed as

AlloysAnti-Bacterial AgentsEscherichia coliLasersProstheses and ImplantsSilverStaphylococcus aureusSurface PropertiesTitaniumAnimalsCalcification, PhysiologicMetal NanoparticlesMicrobial Sensitivity TestsAlloysAnti-Bacterial AgentsSilverTitaniumtitanium alloy (TiAl6V4)

Identifiers

PMID38644661
PMCPMC11078329
OpenAlexW4395005434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.