Evidence map›Paper›PMID 38644429›Full record

ArticleArchives of virology2024

Genomic characterization of human respiratory syncytial virus circulating in Islamabad, Pakistan, during an outbreak in 2022-2023.

Syed Adnan Haider, Zunera Jamal, Faheem Tahir, Muhammad Salman, Massab Umair

Abstract read
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In one paragraph

Article in Archives of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Syed Adnan HaiderDepartment of Virology, National Institute of Health, Park Rd, Chak Shahzad, Islamabad, 45500, Pakistan.
Zunera JamalDepartment of Virology, National Institute of Health, Park Rd, Chak Shahzad, Islamabad, 45500, Pakistan.
Faheem TahirDepartment of Virology, National Institute of Health, Park Rd, Chak Shahzad, Islamabad, 45500, Pakistan.
Muhammad SalmanDepartment of Virology, National Institute of Health, Park Rd, Chak Shahzad, Islamabad, 45500, Pakistan.
Massab UmairDepartment of Virology, National Institute of Health, Park Rd, Chak Shahzad, Islamabad, 45500, Pakistan. massab.umair@yahoo.com.ORCID http://orcid.org/0000-0003-4540-8467
National Institute of Health · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, conducted at the National Institute of Health, Islamabad, during an outbreak of human respiratory syncytial virus (hRSV) from December 2022 to January 2023, the first whole-genome sequences of hRSV isolates from Islamabad, Pakistan, were determined. Out of 10 positive samples, five were sequenced, revealing the presence of two genotypes: RSV-A (GA2.3.5, ON1 strain) and RSV-B (GB5.0.5.a, BA-10 strain). A rare non-synonymous substitution (E232G) in G the protein and N276S in the F protein were found in RSV-A. In RSV-B, the unique mutations K191R, Q209R, and I206M were found in the F protein. These mutations could potentially influence vaccine efficacy and viral pathogenicity. This research underscores the importance of genomic surveillance for understanding RSV diversity and guiding public health responses in Pakistan.

Indexed as

Disease OutbreaksGenome, ViralGenotypePhylogenyRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsChild, PreschoolFemaleGenomicsHumansInfantMaleMutationPakistanViral Fusion ProteinsWhole Genome SequencingViral Fusion Proteins

Identifiers

PMID38644429
OpenAlexW4395009002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.