ArticleScientific reports2024
Risk factors for early-onset adjacent segment degeneration after one-segment posterior lumbar interbody fusion.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Development and validation of explainable machine learning models to predict the risk of adjacent segment disease after lumbar fusion surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Low-Profile Posterior Lumbar Fusion Combined With Proximal Interlaminar Coflex Dynamic Fixation for Lumbar Degenerative Diseases: A Comparative Study.Orthopaedic surgery · 2026Article
- Systemic inflammation and adjacent segment disease after lumbar fusion: the importance of biomarker timing.Quantitative imaging in medicine and surgery · 2026Article
- Could alteration in the vacuum phenomenon rather than its presence be a sign of spinal instability?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Long-term Performance and Durability of Biomaterials and Implant Designs in Total Joint Arthroplasty and Spinal Fusion.Journal of orthopaedics and sports medicine · 2026Article
- Radiographic Analysis of Early Changes in Upper Adjacent Segments After Fusion Surgery: OLIF vs. PLIF.Journal of clinical medicine · 2025Article
- Do all symptomatic adjacent segment diseases (ASD) require surgery? a prognostic classification and predictors of surgical treatment of lumbar ASD.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Risk factors and treatment strategies for adjacent segment disease following spinal fusion (Review).Molecular medicine reports · 2025Review
- Clinical and radiologic evaluation of the IntraSPINE non-fusion technique for lumbar degenerative disease.American journal of translational research · 2025Article
- L5 spondylolysis increases segmental mobility at the cranial adjacent level without altering intervertebral disc contact pressure.Frontiers in bioengineering and biotechnology · 2025Article
- Development and validation of a nomogram to predict the risk of adjacent segment disease after transforaminal lumbar interbody fusion in patients with lumbar degenerative diseases.Journal of orthopaedic surgery and research · 2024Article
- Mismatch Between Pelvic Incidence and Lumbar Lordosis After Personalized Interbody Fusion: The Importance of Preoperative Planning and Alignment in Degenerative Spine Diseases.International journal of spine surgery · 2024Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Adjacent segment degeneration (ASD) is a major postoperative complication associated with posterior lumbar interbody fusion (PLIF). Early-onset ASD may differ pathologically from late-onset ASD. The aim of this study was to identify risk factors for early-onset ASD at the cranial segment occurring within 2 years after surgery. A retrospective study was performed for 170 patients with L4 degenerative spondylolisthesis who underwent one-segment PLIF. Of these patients, 20.6% had early-onset ASD at L3-4. In multivariate logistic regression analysis, preoperative larger % slip, vertebral bone marrow edema at the cranial segment on preoperative MRI (odds ratio 16.8), and surgical disc space distraction (cut-off 4.0 mm) were significant independent risk factors for early-onset ASD. Patients with preoperative imaging findings of bone marrow edema at the cranial segment had a 57.1% rate of early-onset ASD. A vacuum phenomenon and/or concomitant decompression at the cranial segment, the degree of surgical reduction of slippage, and lumbosacral spinal alignment were not risk factors for early-onset ASD. The need for fusion surgery requires careful consideration if vertebral bone marrow edema at the cranial segment adjacent to the fusion segment is detected on preoperative MRI, due to the negative impact of this edema on the incidence of early-onset ASD.
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