SynthesisThe journal of nutrition, health & aging2024
Effects of physical training on depression and related quality of life in pre-frail and frail older adults: a systematic review and meta-analysis.
Synthesis in The journal of nutrition, health & aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Effects of motor-cognitive training on cognitive function and gait performance in older adults with dementia: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Effects of traditional fitness qigong exercise on frailty status and overall well-being in frail or pre-frail patients: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Frailty domains and quality of life associated with geriatric depression in Brazilian primary health care: a cross-sectional study.Scientific reports · 2026Article
- Quality of Life, Social Networking, and Mental Health: Generational Differentiation and Uniqueness in the Context of South Korea.Journal of clinical medicine · 2025Article
- Suicide in later life: the role of frailty and depression.Current opinion in psychiatry · 2025Review
- Association of lifestyle modifications with frailty in older adults: A cross-sectional study using NHANES.The Journal of frailty & aging · 2025Article
- Connecting the dots: sex, depression, and musculoskeletal health.The Journal of clinical investigation · 2024Review
- Motivational Barriers and Facilitators for Older Adults' Engagement in Exercise during Depressive Episodes: A Network Meta-Analysis of Randomized Controlled Trials.Healthcare (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the effects of physical training on depression and related quality of life in pre-frail and frail individuals.
designA systematic review and meta-analysis.
participantsPre-frail and frail older adults.
methodsFive electronic databases, including PubMed, Cochrane, Medline, CINAHL, and Wiley were searched through December 2023. Randomized controlled trials (RCT) comparing physical training with usual care, health education, or light-intensity exercise were included. Outcomes included depression and depression-related quality of life. The quality of the included studies was assessed using Physiotherapy Evidence Database (PEDro) score, and the Cochrane Risk of Bias Tool was used to assess the risk of bias. Meta-analysis was performed using the RevMan5.4. The certainty of the evidence was evaluated by The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach.
resultsTen articles with 589 participants met the inclusion criteria and were included. The pooled analysis indicated that depression (SMD = -0.55, 95%CI = -0.92, -0.17, p = 0.004) and mental health status in life (SMD = 1.05, 95%CI = 0.59, 1.50, p < 0.00001) improved significantly in the experimental group. The results of subgroup analysis revealed that the beneficial effects of physical training were significant only in frail older adults but not in pre-frail older adults.
conclusionThis meta-analysis showed that the positive effects of physical training on depression and related quality of life were evident for people with frailty. However, no positive results were observed in pre-frail older adults, indicating the need for further investigation in this subgroup.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.