Evidence map›Paper›PMID 38643339›Full record

ArticleBritish journal of cancer2024

Tumour-associated myeloid cells expressing IL-10R2/IL-22R1 as a potential biomarker for diagnosis and recurrence of pancreatic ductal adenocarcinoma.

Hyung Keun Lee, So Young Kim, Soo-Hyun Chung, Bongkun Choi, Ji-Eun Kim, Dohee Yoon, Sung Ill Jang, Areum Yeo, Hyun Goo Kang, Jusung Lee and 6 more

Open access · hybridAbstract read
In one paragraph

Article in British journal of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Hyung Keun LeeSeverance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, Seoul, Korea.
So Young KimSeverance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, Seoul, Korea.
Soo-Hyun ChungDepartment of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0003-2808-1327
Bongkun ChoiDepartment of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Ji-Eun KimDepartment of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Dohee YoonDepartment of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Sung Ill JangDepartment of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Areum YeoSeverance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, Seoul, Korea.
Hyun Goo KangInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
Jusung LeeDepartment of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
Yoon Ha ChoiDepartment of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
Joon Seong ParkDepartment of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Yoolim SungDepartment of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Jong Kyoung Kim *Department of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, Korea. blkimjk@postech.ac.kr.ORCID 0000-0002-0257-0547
Eun-Ju Chang *Department of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. ejchang@amc.seoul.kr.ORCID 0000-0001-8324-5406
Dong Ki Lee *Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. dklee@yuhs.ac.ORCID 0000-0002-0048-9112
Ulsan College · KRYonsei University · KRPohang University of Science and Technology · KRSeoul National University · KR

Funding

Ministry of Science, ICT and Future Planning (MSIP) 2022R1A2C1009522Ministry of Science, ICT and Future Planning (MSIP) 2023R1A2C3004065National Research Foundation of Korea (NRF) 2018R1A5A2020732
6 · The paper itself

Abstract

backgroundPancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a poor survival rate, largely due to the lack of early diagnosis. Although myeloid cells are crucial in the tumour microenvironment, whether their specific subset can be a biomarker of PDAC progression is unclear.

methodsWe analysed IL-22 receptor expression in PDAC and peripheral blood. Additionally, we analysed gene expression profiles of IL-10R2

resultsIL-10R2

conclusionsIL-10R2

Indexed as

Biomarkers, TumorCarcinoma, Pancreatic DuctalInterleukin-10 Receptor beta SubunitMyeloid CellsNeoplasm Recurrence, LocalPancreatic NeoplasmsReceptors, InterleukinAnimalsCell Line, TumorFemaleHumansMaleMiceTumor MicroenvironmentBiomarkers, TumorIL10RB protein, humanInterleukin-10 Receptor beta Subunitinterleukin-22 receptorReceptors, Interleukin

Identifiers

PMID38643339
PMCPMC11183123
OpenAlexW4394987455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.