Evidence map›Paper›PMID 38643338›Full record

ArticleBritish journal of cancer2024

Vaccination and screening strategies to accelerate cervical cancer elimination in Norway: a model-based analysis.

Allison Portnoy, Kine Pedersen, Jane J Kim, Emily A Burger

Open access · greenAbstract read
In one paragraph

Article in British journal of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Allison PortnoyDepartment of Global Health, Boston University School of Public Health, Boston, MA, USA. aportnoy@bu.edu.ORCID 0000-0002-8467-1324
Kine PedersenDepartment of Health Management and Health Economics, University of Oslo, Oslo, Norway.ORCID 0000-0002-4923-0670
Jane J KimCenter for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Emily A BurgerCenter for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
University of Oslo · NOBoston University · US

Funding

Kreftforeningen (Norwegian Cancer Society) 198073
6 · The paper itself

Abstract

backgroundExperts have proposed an 'EVEN FASTER' concept targeting age-groups maintaining circulation of human papillomavirus (HPV). We explored effects of the vaccination component of these proposals compared with cervical cancer (CC) screening-based interventions on age-standardized incidence rate (ASR) and CC elimination (<4 cases/100,000) timing in Norway.

methodsWe used a model-based approach to evaluate HPV vaccination and CC screening scenarios compared with a status-quo scenario reflecting previous vaccination and screening. For cohorts ages 25-30 years, we examined 6 vaccination scenarios that incrementally increased vaccination coverage from current cohort-specific rates. Each vaccination scenario was coupled with three screening strategies that varied screening frequency. Additionally, we included 4 scenarios that alternatively increased screening adherence. Population- and cohort-level outcomes included ASR, lifetime risk of CC, and colposcopy referrals.

resultsSeveral vaccination strategies coupled with de-intensified screening frequencies lowered ASR, but did not accelerate CC elimination. Alternative strategies that increased screening adherence could both accelerate elimination and improve ASR.

conclusionsThe vaccination component of an 'EVEN FASTER' campaign is unlikely to accelerate CC elimination in Norway but may reduce population-level ASR. Alternatively, targeting under- and never-screeners may both eliminate CC faster and lead to greater health benefits compared with vaccination-based interventions we considered.

Indexed as

Early Detection of CancerPapillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsVaccinationAdultFemaleHumansIncidenceMass ScreeningNorwayPapillomavirus Vaccines

Identifiers

PMID38643338
PMCPMC11183251
OpenAlexW4394988901

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.