Evidence map›Paper›PMID 38643302›Full record

ArticleScientific reports2024

Hemoglobin levels are associated with retinal vascular caliber in a middle-aged birth cohort.

Samuli Sakko, Mikko Karpale, Joona Tapio, Iina Leppänen, Oona Ahokas, Ville Saarela, M Johanna Liinamaa, Peppi Koivunen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Samuli SakkoBiocenter Oulu and Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, P.O. Box 5400, 90014, Oulu, Finland.
Mikko KarpaleBiocenter Oulu and Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, P.O. Box 5400, 90014, Oulu, Finland.
Joona TapioBiocenter Oulu and Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, P.O. Box 5400, 90014, Oulu, Finland.
Iina LeppänenDepartment of Ophthalmology, Medical Research Center Oulu and Research Unit of Clinical Medicine, Oulu University Hospital, University of Oulu, Oulu, Finland.
Oona AhokasDepartment of Ophthalmology, Medical Research Center Oulu and Research Unit of Clinical Medicine, Oulu University Hospital, University of Oulu, Oulu, Finland.
Ville SaarelaDepartment of Ophthalmology, Medical Research Center Oulu and Research Unit of Clinical Medicine, Oulu University Hospital, University of Oulu, Oulu, Finland.
M Johanna LiinamaaDepartment of Ophthalmology, Medical Research Center Oulu and Research Unit of Clinical Medicine, Oulu University Hospital, University of Oulu, Oulu, Finland. johanna.liinamaa@oulu.fi.
Peppi KoivunenBiocenter Oulu and Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, P.O. Box 5400, 90014, Oulu, Finland. peppi.koivunen@oulu.fi.
University of Oulu · FIOulu University Hospital · FI

Funding

Academy of Finland 308009Jane ja Aatos Erkon Säätiö PKOulu University Hospital VTR funding JL, VSSigrid Juselius Foundation PKSilmäsäätiö,Finland VS, JLSokeain ystävät ry SS
6 · The paper itself

Abstract

Vascular and neural structures of the retina can be visualized non-invasively and used to predict ocular and systemic pathologies. We set out to evaluate the association of hemoglobin (Hb) levels within the national reference interval with retinal vascular caliber, optical coherence tomography (OCT) and visual field (VF) parameters in the Northern Finland 1966 Birth Cohort (n = 2319, 42.1% male, average age 47 years). The studied parameters were evaluated in Hb quintiles and multivariable linear regression models. The lowest Hb quintile of both sexes presented the narrowest central retinal vein equivalent (CRVE) and the healthiest cardiometabolic profile compared to the other Hb quintiles. In the regression models, CRVE associated positively with Hb levels in both sexes, (B

Indexed as

Cardiovascular DiseasesEye DiseasesBirth CohortFemaleHemoglobinsHumansMaleMiddle AgedRetinaRetinal VesselsHemoglobins

Identifiers

PMID38643302
PMCPMC11032340
OpenAlexW4394979975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.