Evidence map›Paper›PMID 38642210›Full record

ArticleInternational urology and nephrology2024

Effects of tacrolimus on proteinuria in Chinese and Indian patients with idiopathic membranous nephropathy: the results of machine learning study.

Min Rui, Lei Jiang, Jia-Jun Pan, Xue-Ting Huang, Jia-Fang Cui, Shi-Jia Zhang, Su-Mei He, Huan-Huan Han, Xiao Chen, Dong-Dong Wang

Abstract read
PubMed Publisher
In one paragraph

Article in International urology and nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Min Rui *Department of Orthopaedics, The Affiliated Jiangyin Clinical College of Xuzhou Medical University, Jiangyin, 214400, Jiangsu, China.
Lei Jiang *Department of Pharmacy, Taixing People's Hospital, Taixing, 225400, Jiangsu, China.
Jia-Jun Pan *Department of Thoracic Cardiovascular Surgery, The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, Xuzhou, 221100, Jiangsu, China.
Xue-Ting Huang *Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy and School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Jia-Fang CuiJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy and School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Shi-Jia ZhangJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy and School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Su-Mei HeDepartment of Pharmacy, Suzhou Hospital, Affiliated Hospital of Medical School, Nanjing University, Suzhou, 215153, Jiangsu, China. hehe8204@163.com.
Huan-Huan HanDepartment of Pharmacy, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, 222000, Jiangsu, China. 18961321750@163.com.
Xiao ChenSchool of Nursing, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China. chenxiao112733@163.com.
Dong-Dong WangJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy and School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China. 13852029591@163.com.ORCID http://orcid.org/0000-0002-4019-5530
Xuzhou Medical College · CNSuzhou Municipal Hospital · CNTaixing People's Hospital · CN

Funding

Innovation Program in Military Medicine of Chinese People's Liberation Army XYRHCX2021011The Fusion Innovation Project of Xuzhou Medical University XYRHCX2022005The Initializing Fund of Xuzhou Medical University RC20552111The Initializing Fund of Xuzhou Medical University RC20552222The Medical Research Project of Jiangsu Provincial Health Commission Z2023010The Xuzhou Special fund for promoting scientific and technological innovation KC23254
6 · The paper itself

Abstract

purposeThe present study aims to explore the effects of tacrolimus on proteinuria in patients with idiopathic membranous nephropathy (IMN) and recommend an appropriate dosage schedule via machine learning method.

methodsThe E

resultsIn machine learning model, the E

conclusionFor achieving better therapeutic effects from tacrolimus on proteinuria in patients with IMN, tacrolimus concentration range need to be maintained at 4-10 ng/ml for at least 1.72 months.

Indexed as

Glomerulonephritis, MembranousImmunosuppressive AgentsMachine LearningProteinuriaTacrolimusAdultChinaEast Asian PeopleFemaleHumansIndiaMaleMiddle AgedSouth Asian PeopleImmunosuppressive AgentsTacrolimusIdiopathic membranous nephropathyMachine learningPredictionProteinuriaTacrolimus

Identifiers

PMID38642210
OpenAlexW4394977586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.