Evidence map›Paper›PMID 38642176›Full record

ArticleBiochemical genetics2025

Association Between CYP24A1 Polymorphisms and Bladder Cancer Risk in the Chinese Han Population.

Tianyi Zhang, Baoping Hu, Shilin Xu, Yuhe Wang, Hengxun Zhang, Xuemei Li, Xuguang Li, Tianbo Jin, Yongjun He

Abstract read
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In one paragraph

Article in Biochemical genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tianyi Zhang *School of Medicine, Xizang Minzu University, Xianyang, 712082, Shaanxi, China.
Baoping Hu *School of Medicine, Xizang Minzu University, Xianyang, 712082, Shaanxi, China.
Shilin XuSchool of Medicine, Xizang Minzu University, Xianyang, 712082, Shaanxi, China.
Yuhe WangSchool of Medicine, Xizang Minzu University, Xianyang, 712082, Shaanxi, China.
Hengxun ZhangSchool of Medicine, Xizang Minzu University, Xianyang, 712082, Shaanxi, China.
Xuemei LiSchool of Medicine, Xizang Minzu University, Xianyang, 712082, Shaanxi, China.
Xuguang LiSchool of Medicine, Xizang Minzu University, Xianyang, 712082, Shaanxi, China.
Tianbo JinSchool of Medicine, Xizang Minzu University, Xianyang, 712082, Shaanxi, China. jintb@xzmu.edu.cn.
Yongjun HeSchool of Medicine, Xizang Minzu University, Xianyang, 712082, Shaanxi, China. 545139647@qq.com.
Xizang Minzu University · CNMinistry of Education of the People's Republic of China · CN

Funding

Talent Development Supporting Project entitled Tibet-Shaanxi Himalaya of Xizang Minzu University 2020 Plateau Scholar
6 · The paper itself

Abstract

In this cohort of 217 bladder cancer patients and 484 healthy controls, we explored the association between CYP24A1 variants (rs2762934, rs1570669, rs6068816, rs2296241) and bladder cancer risk in the Chinese Han population. Utilizing the Agena MassARRAY system, we genotyped four selected CYP24A1 polymorphisms. Logistic regression revealed a significant association of rs2762934 and rs1570669 with elevated bladder cancer risk, while rs6068816 exhibited a protective effect. Bioinformatics analysis of CYP24A1 expression in normal and cancerous bladder tissues indicated higher expression in normal tissue. In conclusion, our findings highlight the potential role of CYP24A1 variants in bladder cancer susceptibility.

Indexed as

East Asian PeopleGenetic Predisposition to DiseasePolymorphism, Single NucleotideUrinary Bladder NeoplasmsVitamin D3 24-HydroxylaseAgedCase-Control StudiesChinaFemaleHumansMaleMiddle AgedCYP24A1 protein, humanVitamin D3 24-HydroxylaseBladder cancerCase-control studyCYP24A1PolymorphismSusceptibility

Identifiers

PMID38642176
OpenAlexW4394988867

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.