Evidence map›Paper›PMID 38641993›Full record

ReviewJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc2024

Intrahepatic mucinous cholangiocarcinoma with recurrent colic in a horse case report and literature review of cholangiocarcinoma in horses.

Daniel Felipe Barrantes Murillo, Russell C Cattley, John M Cullen, Cornelius Withers, Jordan Towns, Rachel Pfeifle, Anne Wooldridge, Rachel L A L T Neto

Open access · greenAbstract readCase ReportsReview
In one paragraph

Review in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Daniel Felipe Barrantes MurilloDepartments of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.ORCID 0000-0002-0744-3774
Russell C CattleyDepartments of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
John M CullenDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.
Cornelius WithersDepartments of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
Jordan TownsDepartments of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
Rachel PfeifleClinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
Anne WooldridgeClinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
Rachel L A L T NetoDepartments of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
Auburn University · USNorth Carolina State University · USUniversity of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 17-y-old Arabian mare was presented to the Auburn Large Animal Veterinary Teaching Hospital with a long-term history of intermittent mild recurrent colic that responded to medical treatment. CBC revealed mild lymphopenia; serum biochemistry findings were of increased gamma-glutamyl transferase and creatine kinase activities, hyperferremia, hyperglycemia, hypomagnesemia, and hypokalemia. Abdominocentesis was compatible with low-protein transudate. Due to the progression and duration of clinical signs, the owner elected euthanasia. Postmortem examination and histopathology confirmed a cholangiocarcinoma. The neoplastic cells were arranged in large cysts containing lakes of mucin that comprised 90% of the tumor volume; thus, a mucinous variant was determined. The neoplastic cells had strong cytoplasmic immunolabeling for cytokeratin 19 and lacked immunolabeling for hepatocyte paraffin 1, supporting bile duct origin. Cholangiocarcinomas are infrequent tumors in horses with nonspecific and slow progressive clinical signs, including recurrent colic. Mucinous cholangiocarcinomas are seldom reported in veterinary medicine and, to our knowledge, have not been reported previously in horses.

Indexed as

Adenocarcinoma, MucinousBile Duct NeoplasmsCholangiocarcinomaColicHorse DiseasesLiverAnimalsFemaleHorsescytokeratin 19HepPar1horsesmucinous cholangiocarcinomaneoplasia

Identifiers

PMID38641993
PMCPMC11185110
OpenAlexW4394975845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.