ArticleBMC musculoskeletal disorders2024
Global burden of osteoarthritis in adults aged 30 to 44 years, 1990 to 2019: results from the Global Burden of Disease Study 2019.
Article in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 34 citations in OpenAlex.
- Associations of health parameters at 16 years of age with structural knee MRI findings at 33 years of age in a general population-based birth cohort.Osteoarthritis and cartilage open · 2026Article
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- IMMT downregulation promotes osteoarthritis development by inducing mitochondrial dysfunction.Journal of orthopaedic surgery and research · 2026Article
- Associations of clinical measures and structural knee magnetic resonance imaging findings with knee symptoms in a birth cohort of 33-year-old adults.Osteoarthritis and cartilage open · 2026Article
- Osteoimmunology and aging - a frontier to explore.GeroScience · 2026Review
- Burden and Temporal Trends of Osteoarthritis in Germany from 1990 to 2021, with Projections to 2041: Findings from the Global Burden of Disease Study.Orthopedic research and reviews · 2026Article
- Hip Osteoarthritis and the Human Microbiome: Current Concepts, Biological Insights and Future Directions.Orthopedic reviews · 2026Article
- Adipose-derived mesenchymal stem cells for early hip osteoarthritis: mechanistic insights and possible clinical evidence.Frontiers in surgery · 2026Review
- Electroacupuncture alleviates osteoarthritis and is associated with changes in gut microbiota and steroid biosynthesis-related metabolites.Frontiers in molecular biosciences · 2026Article
- Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications.Molecular medicine reports · 2026Article
- A novel approach for longitudinal analysis of serum biomarkers of joint metabolism and knee injury in military officers.PloS one · 2026Article
- An experimental-computational approach for measuring charged solute diffusivity through human synovium.Journal of biomechanics · 2025Article
- Correlation between Kellgren-Lawrence classification of osteoarthritis and Knee Injury and Osteoarthritis Outcome Score.World journal of orthopedics · 2025Article
- Clinical Outcomes Following Medial Opening Wedge High Tibial Osteotomy in Patients With Medial Compartment Grade 4 Chondromalacia.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Article
- Comparative outcome analyses of stromal vascular fractionWorld journal of experimental medicine · 2025Article
- Gender differences in the burden of near vision loss in China: An analysis based on GBD 2021 data.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Global, regional, and national burden of refraction disorders: findings from the global burden of disease study 2021 and projections to 2050.BMC public health · 2025Article
- Analgesic and anti-inflammatory effects of chicken feet combined with traditional herbal medicines in acetic acid-induced mice and monosodium iodoacetate-induced osteoarthritis rats.Food science and biotechnology · 2025Article
- Orthobiologic injections for hip osteoarthritis: A systematic review of clinical outcomes.Orthopedic reviews · 2025Article
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOsteoarthritis (OA) is a common orthopedic disorder, and its incidence has been increasing among young adults in recent years. The purpose of this study is to investigate the global, regional, and national trends in OA burden and variation among individuals aged 30 to 44 from 1990 to 2019.
methodsData on the incidence, prevalence, and years lived with disability (YLDs) related to OA were sourced from the Global Burden of Disease Study 2019 among individuals aged 30 to 44. These measures were stratified by gender, region, country, and socio-demographic index (SDI). Additionally, we analyzed YLDs attributable to risk factors.
resultsIn 2019, there were a total of 32,971,701 cases of OA among individuals aged 30 to 44 years worldwide, with an additional 7,794,008 new incident cases reported. OA of the knee was the primary contributor to both incidence and prevalence rates over the past three decades. From 1990 to 2019, both males and females in countries with high SDI and high-middle SDI showed upward trends in age-standardized incidence, prevalence, and YLDs rates. In 2019, the United States of America had the highest age-standardized incidence, prevalence, and YLDs rates. Elevated body-mass index (BMI) was found to be the most prevalent risk factor for osteoarthritis-related YLDs. Age-standardized YLDs rates were positively associated with SDI.
conclusionsOA remains a significant disease burden on individuals aged 30 to 44, with modifiable risk factors such as unhealthy lifestyle and obesity representing key targets for future interventions aimed at reducing the impact of this condition on younger generations.
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