Evidence map›Paper›PMID 38640643›Full record

ArticleBrain and language2024

Language processing following childhood poverty: Evidence for disrupted neural networks.

Suzanne C Perkins, S Shaun Ho, Gary W Evans, Israel Liberzon, Meroona Gopang, James E Swain

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain and language, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Suzanne C PerkinsResearch Center for Group Dynamics, Institute for Social Research, University of Michigan, Ann Arbor, MI 48106, United States. Electronic address: sperkinz@umich.edu.
S Shaun HoDepartment of Psychiatry and Behavioral Health, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794-8434, United States.
Gary W EvansDepartments of Human Centered Design and Psychology, Cornell University, Ithaca, NY 14853-4401, United States.
Israel LiberzonDepartment of Psychiatry, Texas A&M University, Bryan, TX 77802, United States.
Meroona GopangDepartment of Psychiatry and Behavioral Health, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794-8434, United States; Program in Public Health, Department of Psychiatry and Behavioral Health, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794-8434, United States.
James E SwainDepartment of Psychiatry and Behavioral Health, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794-8434, United States; Psychology, Obstetrics, Gynecology & Reproductive Medicine, Program in Public Health, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794-8434, United States.
Stony Brook School · USCornell University · USStony Brook University · USTexas A&M University · USUniversity of Michigan · US

Funding

Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
The Center for Innovation in Child Maltreatment Policy Research and Training (CICM) Community Engagement Core (CEC)P50HD096719 · NICHD · WASHINGTON UNIVERSITY · PI CONSTANTINO, JOHN N. · 2018 to 2022
$6.8M
Postpartum Intervention for Mothers with Opioid Use Disorders - Brain-Behavior MechanismsR33DA053688 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI Maria Muzik, James Edward Swain · 2025 to 2026
$1.5M
Childhood Poverty and Brain Development: The Role of Chronic Stress and ParentingRC2MD004767 · NIMHD · CORNELL UNIVERSITY · PI EVANS, GARY W, LIBERZON, ISRAEL · 2009 to 2010
$1.4M
NCATS NIH HHS UL1 TR000433NCIPC CDC HHS R49 CE002099NICHD NIH HHS P50 HD096719NIDA NIH HHS R33 DA053688NIMHD NIH HHS RC2 MD004767
6 · The paper itself

Abstract

Childhood poverty is related to deficits in multiple cognitive domains including adult language function. It is unknown if the brain basis of language is disrupted in adults with childhood poverty backgrounds, controlling for current functioning. Fifty-one adults (age 24) from an existing longitudinal study of childhood poverty, beginning at age 9, were examined on behavioral phonological awareness (LP) and completed an event-related fMRI speech/print processing LP task. Adults from childhood poverty backgrounds exhibited lower LP in adulthood. The middle-income group exhibited greater activation of the bilateral IFG and hippocampus during language processing. In psychophysiological interaction (PPI) analyses, the childhood poverty group exhibited greater coupling between ventral Broca's and the middle temporal gyrus (MTG) as well as coupling between Wernicke's region and bilateralization. Childhood poverty disrupts language processing neural networks in adulthood, after controlling for LP, suggesting that poverty in childhood influences the neurophysiological basis for language processing into adulthood.

Indexed as

BrainLanguageMagnetic Resonance ImagingPovertyAdultBrain MappingChildFemaleHumansLongitudinal StudiesMaleNerve NetYoung AdultFunctional connectivityLongitudinal studyPerisylvian regionPsychophysiological interaction analysisTask-based fMRI

Identifiers

PMID38640643
PMCPMC12581652
OpenAlexW4394912047

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.