Evidence map›Paper›PMID 38640417›Full record

ArticleUrology practice2024

Racial and Ethnic Variation in Receipt and Intensity of Active Surveillance for Older Patients With Localized Prostate Cancer.

Spyridon P Basourakos, Anjile An, Meenakshi Davuluri, Laura C Pinheiro, Bashir Al Hussein Al Awamlh, Leonardo D Borregales, Danny Luan, Rulla M Tamimi, Jim C Hu, Kevin H Kensler

Open access · greenAbstract read
In one paragraph

Article in Urology practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Spyridon P BasourakosDepartment of Urology, NewYork-Presbyterian Hospital-Weill Cornell Medicine, New York, New York.ORCID 0000-0002-7458-4593
Anjile AnDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York.
Meenakshi DavuluriDepartment of Urology, NewYork-Presbyterian Hospital-Weill Cornell Medicine, New York, New York.
Laura C PinheiroDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York.
Bashir Al Hussein Al AwamlhDepartment of Urology, Vanderbilt University Medical Center, Nashville, Tennessee.
Leonardo D BorregalesDepartment of Urology, NewYork-Presbyterian Hospital-Weill Cornell Medicine, New York, New York.
Danny LuanDepartment of Hematology and Oncology, NewYork-Presbyterian Hospital-Weill Cornell Medicine, New York, New York.
Rulla M TamimiDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York.
Jim C HuDepartment of Urology, NewYork-Presbyterian Hospital-Weill Cornell Medicine, New York, New York.
Kevin H KenslerDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York.
Cornell University · USNewYork–Presbyterian Hospital · USMayo Clinic · USVanderbilt University Medical Center · US

Funding

Weill Cornell Medicine (WCM) SPORE in Prostate CancerP50CA211024 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LODA, MASSIMO · 2017 to 2021
$10.9M
Contributions of tumor molecular subtypes to prostate cancer racial disparitiesR00CA245900 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI KENSLER, KEVIN HUGHES · 2021 to 2023
$689k
CDC HHS 1NU58DP007156NCI NIH HHS HHSN261201800009CNCI NIH HHS HHSN261201800009INCI NIH HHS HHSN261201800015CNCI NIH HHS HHSN261201800015INCI NIH HHS HHSN261201800032CNCI NIH HHS HHSN261201800032INCI NIH HHS P50 CA211024NCI NIH HHS R00 CA245900
6 · The paper itself

Abstract

introductionThe use of active surveillance (AS) for prostate cancer is increasing, and racial disparities have been identified in its implementation. We investigated differences by race and ethnicity in the utilization and intensity of AS by race and ethnicity among older men with low- and favorable intermediate-risk prostate cancer, with particular focus on the integration of multiparametric MRI (mpMRI) into AS protocols.

methodsUsing the Surveillance, Epidemiology, and End Results and Medicare fee-for-service linked database, we identified a cohort of men diagnosed between 2010 and 2017 with low- or favorable intermediate-risk prostate cancer. The odds of receiving AS were compared by patient race and ethnicity using multivariable logistic regression models, while the rates of usage of PSA tests, biopsy, and mpMRI within 2 years of diagnosis among men on AS were assessed using multivariable Poisson regression models.

resultsOur cohort included 33,542 men. The proportion of men with low-risk disease who underwent AS increased from 29.5% in 2010 to 51.7% in 2017, while the proportion among men with favorable intermediate disease grew from 11.4% to 17.2%. Hispanic (odds ratio [OR] = 0.68, 95% CI 0.58-0.79) and non-Hispanic Black men (OR = 0.78, 95% CI 0.68-0.89) were less likely to receive AS than non-Hispanic White men for low-risk disease, while non-Hispanic Black men were more likely to receive AS for favorable intermediate disease (OR = 1.21, 95% CI 1.04-1.39). Non-Hispanic Black men receiving AS underwent prostate MRI at a lower rate compared to non-Hispanic White men, regardless of whether they had low-risk (incidence rate ratio = 0.77, 95% CI 0.61-0.97) or favorable intermediate-risk (incidence rate ratio = 0.61, 95% CI 0.44-0.83) disease, respectively.

conclusionsThe overall adoption of AS for low-risk prostate cancer increased among Medicare fee-for-service beneficiaries. However, a significant disparity exists for non-Hispanic Black men, as they exhibit lower rates of AS utilization. Moreover, non-Hispanic Black men are less likely to have access to novel technologies, such as mpMRI, as part of their AS protocols.

Indexed as

Prostatic NeoplasmsWatchful WaitingAgedBlack or African AmericanHispanic or LatinoHumansMaleMedicareUnited StatesWhiteactive surveillancedisparitiesprostate cancer

Identifiers

PMID38640417
PMCPMC12621090
OpenAlexW4394969855

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.