Evidence map›Paper›PMID 38640351›Full record

ArticleJBRA assisted reproduction2024

Management of patients with endometriosis and infertility: laparoscopic treatment and spontaneous pregnancy rate.

Yanina Rodríguez, Esteban Grasso, Lautaro Tessari, Florencia Perotti, Marcela Irigoyen, Antonio Cattaneo, A Gustavo Martínez, Rosanna Ramhorst, Diego Gnocchi

Open access · bronzeAbstract read
In one paragraph

Article in JBRA assisted reproduction, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yanina RodríguezFERTILIS Medicina Reproductiva, Buenos Aires, Argentina.
Esteban GrassoLaboratorio de Inmunofarmacología, Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN) CONICET y Universidad de Buenos Aires, Argentina.
Lautaro TessariFERTILIS Medicina Reproductiva, Buenos Aires, Argentina.
Florencia PerottiFERTILIS Medicina Reproductiva, Buenos Aires, Argentina.
Marcela IrigoyenFERTILIS Medicina Reproductiva, Buenos Aires, Argentina.
Antonio CattaneoFERTILIS Medicina Reproductiva, Buenos Aires, Argentina.
A Gustavo MartínezFERTILIS Medicina Reproductiva, Buenos Aires, Argentina.
Rosanna RamhorstLaboratorio de Inmunofarmacología, Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN) CONICET y Universidad de Buenos Aires, Argentina.
Diego GnocchiFERTILIS Medicina Reproductiva, Buenos Aires, Argentina.
Fecunditas Instituto de Medicina Reproductiva · ARConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversity of Belgrano · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate factors involved in spontaneous pregnancy rate after surgery for endometriosis in patients with endometriosis and infertility.

methodsThis retrospective study spanned from 2014 to 2020 and included a follow-up period of two years of patients with endometriosis-related infertility who underwent laparoscopic surgery. Women aged 25 to 43 years with patent tubes, no/mild male factor and no other infertility factors were selected and grouped according to fertility management as follows: patients immediately prescribed ART (16.5%, ART-p); patients who chose not to undergo ART (83.5%) and achieved spontaneous pregnancy (71.8% SP-p); and patients who first chose not to undergo ART but had it subsequently (28.2%, NSP-p).

resultsA total of 200 patients were analyzed. Of the 167 patients who waited for spontaneous pregnancy, 71.8% achieved it. We observed a tendency of higher endometriosis ASRM scores in the ART-p group compared with patients who waited for spontaneous pregnancy, and lower scores in individuals that achieved spontaneous pregnancy. When we looked at how long it took to achieve pregnancy, we found that individuals in the SP-p group achieved pregnancy in 5.7 months, while subjects in the NSP-p group took 1.8 times longer than their peers in the SP-p group (p<0.001). However, once prescribed ART, the individuals in the NSP-p group achieved pregnancy within a similar time when compared with subjects in the SP-p group. In order to identify individuals that might benefit from ART early on, we performed a multivariable analysis and developed a decision tree (81.3% accuracy and 53.3% sensitivity).

conclusionsThe present results indicated that, after surgery, the majority of patients achieved spontaneous pregnancy. The decision tree proposed in this study allows the early identification of patients who might require ART, thus decreasing the time between surgery and pregnancy and improving overall outcomes.

Indexed as

EndometriosisInfertility, FemaleLaparoscopyPregnancy RateAdultFemaleHumansPregnancyReproductive Techniques, AssistedRetrospective Studiesendometriosislaparoscopic treatmentspontaneous pregnancy rate

Identifiers

PMID38640351
PMCPMC11349262
OpenAlexW4394981505

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.