Evidence map›Paper›PMID 38639398›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Expanding the Palette of SWIR Emitting Nanoparticles Based on Au Nanoclusters for Single-Particle Tracking Microscopy.

Apolline A Simon, Lucie Haye, Abdallah Alhalabi, Quentin Gresil, Blanca Martín Muñoz, Stéphane Mornet, Andreas Reisch, Xavier Le Guével, Laurent Cognet

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Apolline A SimonUniv. Bordeaux, Laboratoire Photonique Numérique et Nanosciences (LP2N), UMR 5298, Talence, F-33400, France.
Lucie HayeUniversité de Strasbourg, CNRS, Laboratoire de Bioimagerie et Pathologies UMR 7021, Strasbourg, F-67000, France.
Abdallah AlhalabiUniversity of Grenoble Alpes, Institute for Advanced Biosciences, INSERM1209/CNRS-UMR5309, Grenoble, F-38700, France.
Quentin GresilUniv. Bordeaux, Laboratoire Photonique Numérique et Nanosciences (LP2N), UMR 5298, Talence, F-33400, France.
Blanca Martín MuñozUniv. Bordeaux, Laboratoire Photonique Numérique et Nanosciences (LP2N), UMR 5298, Talence, F-33400, France.
Stéphane MornetUniv. Bordeaux, CNRS, Bordeaux INP, ICMCB, UMR 5026, Pessac, 33600, France.ORCID https://orcid.org/0000-0002-1115-5812
Andreas ReischUniversité de Strasbourg, CNRS, Laboratoire de Bioimagerie et Pathologies UMR 7021, Strasbourg, F-67000, France.ORCID https://orcid.org/0000-0003-1154-7637
Xavier Le GuévelUniversity of Grenoble Alpes, Institute for Advanced Biosciences, INSERM1209/CNRS-UMR5309, Grenoble, F-38700, France.ORCID https://orcid.org/0000-0003-3634-7762
Laurent CognetUniv. Bordeaux, Laboratoire Photonique Numérique et Nanosciences (LP2N), UMR 5298, Talence, F-33400, France.ORCID https://orcid.org/0000-0002-3573-5387
Centre National de la Recherche Scientifique · FR

Funding

CEREBRAL CHEMISTRY IN DEMENTIA AND AGING--TREATMENTSZ01AG000401 · NIA · AGING · PI SHETTY, H U · 1994 to 1998
–
Agence Nationale de la Recherche ANR-20-CE09-0021-04CNRSEUR LightS&T Graduate Program: PIA 3 Investment for Future Program, ANR-17-EURE-0027European Research Council Synergy 951294France-BioImaging National Infrastructure ANR-10-INBS-04-01France Life Imaging ANR-11-INBS-0006Grand Research Program GPR LIGHTUniversity of Bordeaux
6 · The paper itself

Abstract

Single-molecule localization microscopy has proved promising to unravel the dynamics and molecular architecture of thin biological samples down to nanoscales. For applications in complex, thick biological tissues shifting single-particle emission wavelengths to the shortwave infrared (SWIR also called NIR II) region between 900 to 2100 nm, where biological tissues are more transparent is key. To date, mainly single-walled carbon nanotubes (SWCNTs) enable such applications, but they are inherently 1D objects. Here, 0D ultra-small luminescent gold nanoclusters (AuNCs, <3 nm) and ≈25 nm AuNC-loaded-polymeric particles that can be detected at the single-particle level in the SWIR are presented. Thanks to high brightness and excellent photostability, it is shown that the dynamics of the spherical polymeric particles can be followed at the single-particle level in solution at video rates for minutes. We compared single particle tracking of AuNC-loaded-polymeric particles with that of SWCNT diffusing in agarose gels demonstrating the specificity and complementarity of diffusion properties of these SWIR-emitting nano-objects when exploring a complex environment. This extends the library of photostable SWIR emitting nanomaterials to 0D nano-objects of variable size for single-molecule localization microscopy in the second biological window, opening unprecedented possibilities for mapping the structure and dynamics of complex biological systems.

Indexed as

luminescencenanoparticlephotostabilitysingle particle trackingSWIR imaging

Identifiers

PMID38639398
PMCPMC11199965
OpenAlexW4394962384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.