Evidence map›Paper›PMID 38639371›Full record

ArticleJournal of the American Heart Association2024

Persistent Inequities in Intravenous Thrombolysis for Acute Ischemic Stroke in the United States: Results From the Nationwide Inpatient Sample.

Philip Sun, Ling Zheng, Michelle Lin, Steven Cen, Gmerice Hammond, Karen E Joynt Maddox, May Kim-Tenser, Nerses Sanossian, William Mack, Amytis Towfighi

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Philip SunDepartment of Neurology David Geffen School of Medicine at University of California Los Angeles CA USA.ORCID 0000-0003-4428-6031
Ling ZhengDepartment of Neurology, Keck School of Medicine University of Southern California Los Angeles CA USA.
Michelle LinDepartment of Neurology Mayo Clinic Jacksonville FL USA.ORCID 0000-0002-0219-027X
Steven CenDepartment of Neurology, Keck School of Medicine University of Southern California Los Angeles CA USA.ORCID 0000-0002-7859-8909
Gmerice HammondDepartment of Medicine, Cardiovascular Division Washington University School of Medicine St. Louis MO USA.
Karen E Joynt MaddoxDepartment of Medicine, Cardiovascular Division Washington University School of Medicine St. Louis MO USA.ORCID 0000-0003-3779-8653
May Kim-TenserDepartment of Neurology, Keck School of Medicine University of Southern California Los Angeles CA USA.ORCID 0000-0003-0555-0661
Nerses SanossianDepartment of Neurology David Geffen School of Medicine at University of California Los Angeles CA USA.ORCID 0000-0002-8218-9518
William MackDepartment of Neurological Surgery, Keck School of Medicine University of Southern California Los Angeles CA USA.ORCID 0000-0003-0970-2546
Amytis TowfighiDepartment of Neurology David Geffen School of Medicine at University of California Los Angeles CA USA.ORCID 0000-0002-9565-6787
University of Southern California · USWashington University in St. Louis · USJacksonville College · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
UCLA-UCI Center for Eliminating Cardio-Metabolic Disparities in Multi-Ethnic Populations (UC END-DISPARITIES)P50MD017366 · NIMHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BODEN-ALBALA, BERNADETTE MARIE, BROWN, ARLEEN F. · 2021 to 2025
$17.3M
Recurrent Hemorrhagic Stroke in Minority PopulationsR01NS093870 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI JONATHAN ROSAND, Amytis Towfighi · 2016 to 2026
$12.3M
Cardiovascular Health of Low-Income Working-Age Adults in the US: Health Care Access, Policy, and the PandemicR01HL164561 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Rishi Kumar Wadhera · 2022 to 2026
$3.7M
The Impact of Bundled Payments for Cardiopulmonary Disease on High-Risk PopulationsR01HL143421 · NHLBI · WASHINGTON UNIVERSITY · PI JOYNT MADDOX, KAREN ELLEN · 2019 to 2022
$3.1M
Improving the Quality of Care Provided Through Bundled Payments for Patients with Alzheimer's Disease or Other Forms of Dementia or FrailtyR01AG060935 · NIA · HARVARD SCHOOL OF PUBLIC HEALTH · PI EPSTEIN, ARNOLD, JOYNT MADDOX, KAREN ELLEN · 2019 to 2021
$2.7M
Rural-Urban Disparities In Spillover Effects of COVID-19U01NR020555 · NINR · WASHINGTON UNIVERSITY · PI JOYNT MADDOX, KAREN ELLEN · 2022 to 2024
$1.5M
Observation Stays and Readmissions for Older Adults: Implications for Medicare PoliciesR01AG063759 · NIA · UNIVERSITY OF WASHINGTON · PI SABBATINI, AMBER KATHLEEN · 2020 to 2023
$1.4M
The Effect of Patient Dementia on Outpatient Clinicians' Performance on Cost Outcomes Under Medicare Value-Based Payment.R21AG065526 · NIA · WASHINGTON UNIVERSITY · PI JOHNSTON, KENTON JAMES · 2020 to 2021
$308k
NCATS NIH HHS UL1 TR002345NHLBI NIH HHS R01 HL143421NHLBI NIH HHS R01 HL164561NIA NIH HHS R01 AG060935NIA NIH HHS R01 AG063759NIA NIH HHS R21 AG065526NIMHD NIH HHS P50 MD017366NINDS NIH HHS R01 NS093870NINR NIH HHS U01 NR020555
6 · The paper itself

Abstract

backgroundDespite its approval for acute ischemic stroke >25 years ago, intravenous thrombolysis (IVT) remains underused, with inequities by age, sex, race, ethnicity, and geography. Little is known about IVT rates by insurance status. METHODS AND

resultsWe assessed temporal trends from 2002 to 2015 in IVT for acute ischemic stroke in the Nationwide Inpatient Sample using adjusted, survey

conclusionsIVT for acute ischemic stroke increased among adults. Despite some encouraging trends, the remaining disparities highlight the need for intensified efforts at addressing inequities.

Indexed as

Fibrinolytic AgentsHealthcare DisparitiesIschemic StrokeThrombolytic TherapyAdministration, IntravenousAdolescentAdultAgedAged, 80 and overFemaleHumansInpatientsInsurance CoverageMaleMiddle AgedTime FactorsFibrinolytic Agentsepidemiologyethnicityinequitiessex differencesthrombolysis

Identifiers

PMID38639371
PMCPMC11179951
OpenAlexW4394962534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.